HIF2α inhibits glutaminase clustering in mitochondria to sustain growth of clear cell renal cell carcinoma.
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| Title: | HIF2α inhibits glutaminase clustering in mitochondria to sustain growth of clear cell renal cell carcinoma. |
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| Authors: | Zhao W; Department of Medicine, Cardiovascular Institute, and Institute of Diabetes Obesity and Metabolism, and., Demczyszyn SM; The Abramson Family Cancer Research Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Coffey NJ; The Abramson Family Cancer Research Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Jiang Y; The Abramson Family Cancer Research Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Kim B; McAllister Heart Institute, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA., Bowers S; McAllister Heart Institute, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA., Bowman C; Biology Department, Williams College, Williamstown, Massachusetts, USA., Noji MC; The Abramson Family Cancer Research Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Jang C; Department of Biological Chemistry, School of Medicine, University of California, Irvine, California, USA., Simon MC; The Abramson Family Cancer Research Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Arany Z; Department of Medicine, Cardiovascular Institute, and Institute of Diabetes Obesity and Metabolism, and., Kim B; Department of Pathology and Laboratory Medicine, McAllister Heart Institute, Nutrition Obesity Research Center, and Lineberger Cancer Center, University of North Carolina, Chapel Hill, North Carolina, USA. |
| Source: | JCI insight [JCI Insight] 2025 Oct 30; Vol. 10 (23). Date of Electronic Publication: 2025 Oct 30 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41165759 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: HIF2α inhibits glutaminase clustering in mitochondria to sustain growth of clear cell renal cell carcinoma. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Zhao+W%22">Zhao W</searchLink>; Department of Medicine, Cardiovascular Institute, and Institute of Diabetes Obesity and Metabolism, and.<br /><searchLink fieldCode="AU" term="%22Demczyszyn+SM%22">Demczyszyn SM</searchLink>; The Abramson Family Cancer Research Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Coffey+NJ%22">Coffey NJ</searchLink>; The Abramson Family Cancer Research Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+Y%22">Jiang Y</searchLink>; The Abramson Family Cancer Research Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Kim+B%22">Kim B</searchLink>; McAllister Heart Institute, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Bowers+S%22">Bowers S</searchLink>; McAllister Heart Institute, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Bowman+C%22">Bowman C</searchLink>; Biology Department, Williams College, Williamstown, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Noji+MC%22">Noji MC</searchLink>; The Abramson Family Cancer Research Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Jang+C%22">Jang C</searchLink>; Department of Biological Chemistry, School of Medicine, University of California, Irvine, California, USA.<br /><searchLink fieldCode="AU" term="%22Simon+MC%22">Simon MC</searchLink>; The Abramson Family Cancer Research Institute, Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Arany+Z%22">Arany Z</searchLink>; Department of Medicine, Cardiovascular Institute, and Institute of Diabetes Obesity and Metabolism, and.<br /><searchLink fieldCode="AU" term="%22Kim+B%22">Kim B</searchLink>; Department of Pathology and Laboratory Medicine, McAllister Heart Institute, Nutrition Obesity Research Center, and Lineberger Cancer Center, University of North Carolina, Chapel Hill, North Carolina, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101676073%22">JCI insight</searchLink> [JCI Insight] 2025 Oct 30; Vol. 10 (23). <i>Date of Electronic Publication: </i>2025 Oct 30 (<i>Print Publication: </i>2025). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Clinical+Investigation%22">American Society for Clinical Investigation </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101676073 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2379-3708 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223793708%22">23793708 </searchLink><i>NLM ISO Abbreviation: </i>JCI Insight <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41165759 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1172/jci.insight.182711 Languages: – Code: eng Text: English Titles: – TitleFull: HIF2α inhibits glutaminase clustering in mitochondria to sustain growth of clear cell renal cell carcinoma. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Zhao W – PersonEntity: Name: NameFull: Demczyszyn SM – PersonEntity: Name: NameFull: Coffey NJ – PersonEntity: Name: NameFull: Jiang Y – PersonEntity: Name: NameFull: Kim B – PersonEntity: Name: NameFull: Bowers S – PersonEntity: Name: NameFull: Bowman C – PersonEntity: Name: NameFull: Noji MC – PersonEntity: Name: NameFull: Jang C – PersonEntity: Name: NameFull: Simon MC – PersonEntity: Name: NameFull: Arany Z – PersonEntity: Name: NameFull: Kim B IsPartOfRelationships: – BibEntity: Dates: – D: 30 M: 10 Text: 2025 Oct 30 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2379-3708 Numbering: – Type: volume Value: 10 – Type: issue Value: 23 Titles: – TitleFull: JCI insight Type: main |
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