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Plasma extracellular vesicle proteomics identifies FN1/F13A1-TGF-β pathway as the major signaling pathway associated with persistent atrial fibrillation.

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Title: Plasma extracellular vesicle proteomics identifies FN1/F13A1-TGF-β pathway as the major signaling pathway associated with persistent atrial fibrillation.
Authors: Zhang LL; Department of Cardiovascular Surgery & The Institute of Cardiovascular Diseases, TEDA International Cardiovascular Hospital, Tianjin University, Tianjin 300457, China; Tianjin Key Laboratory of Molecular Regulation of Cardiovascular Diseases, Tianjin, China; TEDA International Cardiovascular Hospital, Chinese Academy of Medical Sciences, China., Lin WH; Tianjin Key Laboratory of Molecular Regulation of Cardiovascular Diseases, Tianjin, China; TEDA International Cardiovascular Hospital, Chinese Academy of Medical Sciences, China; Department of Cardiology & The Institute of Cardiovascular Diseases, TEDA International Cardiovascular Hospital, Tianjin University & Chinese Academy of Medical Science, Tianjin 300457, China., Ye Di C; Tianjin Key Laboratory of Molecular Regulation of Cardiovascular Diseases, Tianjin, China; TEDA International Cardiovascular Hospital, Chinese Academy of Medical Sciences, China; Department of Cardiology & The Institute of Cardiovascular Diseases, TEDA International Cardiovascular Hospital, Tianjin University & Chinese Academy of Medical Science, Tianjin 300457, China., Hou HT; Department of Cardiovascular Surgery & The Institute of Cardiovascular Diseases, TEDA International Cardiovascular Hospital, Tianjin University, Tianjin 300457, China; Tianjin Key Laboratory of Molecular Regulation of Cardiovascular Diseases, Tianjin, China; TEDA International Cardiovascular Hospital, Chinese Academy of Medical Sciences, China., Chen HX; Department of Cardiovascular Surgery & The Institute of Cardiovascular Diseases, TEDA International Cardiovascular Hospital, Tianjin University, Tianjin 300457, China; Tianjin Key Laboratory of Molecular Regulation of Cardiovascular Diseases, Tianjin, China; TEDA International Cardiovascular Hospital, Chinese Academy of Medical Sciences, China., Zhou J; Department of Cardiovascular Surgery & The Institute of Cardiovascular Diseases, TEDA International Cardiovascular Hospital, Tianjin University, Tianjin 300457, China; Tianjin Key Laboratory of Molecular Regulation of Cardiovascular Diseases, Tianjin, China., Yang Q; Department of Cardiovascular Surgery & The Institute of Cardiovascular Diseases, TEDA International Cardiovascular Hospital, Tianjin University, Tianjin 300457, China; Tianjin Key Laboratory of Molecular Regulation of Cardiovascular Diseases, Tianjin, China; TEDA International Cardiovascular Hospital, Chinese Academy of Medical Sciences, China., He GW; Department of Cardiovascular Surgery & The Institute of Cardiovascular Diseases, TEDA International Cardiovascular Hospital, Tianjin University, Tianjin 300457, China; Tianjin Key Laboratory of Molecular Regulation of Cardiovascular Diseases, Tianjin, China; TEDA International Cardiovascular Hospital, Chinese Academy of Medical Sciences, China. Electronic address: gwhe@tju.edu.cn.
Source: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2026 Jan 15; Vol. 268, pp. 117211. Date of Electronic Publication: 2025 Oct 25.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-264X
DOI:10.1016/j.jpba.2025.117211