Understanding the molecular basis of mesenchymal stem cell stemness: implications for clinical applications.

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Title: Understanding the molecular basis of mesenchymal stem cell stemness: implications for clinical applications.
Authors: Liu TM; Institute of Molecular and Cell Biology (IMCB), Agency for Science Technology and Research (A*STAR), Singapore, Singapore. dbsliutm@yahoo.com., Tew W; Institute of Molecular and Cell Biology (IMCB), Agency for Science Technology and Research (A*STAR), Singapore, Singapore., Yang Z; Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; NUS Tissue Engineering Program, Life Sciences Institute, National University of Singapore, Singapore, Singapore., Lim B; Thymmune Therapeutics Inc., Cambridge, MA, USA., Hui JHP; Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; NUS Tissue Engineering Program, Life Sciences Institute, National University of Singapore, Singapore, Singapore., Lee EH; Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; NUS Tissue Engineering Program, Life Sciences Institute, National University of Singapore, Singapore, Singapore., Loh YH; Institute of Molecular and Cell Biology (IMCB), Agency for Science Technology and Research (A*STAR), Singapore, Singapore. jonathan_loh@a-star.edu.sg., Cool S; Institute of Molecular and Cell Biology (IMCB), Agency for Science Technology and Research (A*STAR), Singapore, Singapore. s.cool@uq.edu.au.; Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. s.cool@uq.edu.au.; School of Chemical Engineering, University of Queensland, Brisbane, QLD, Australia. s.cool@uq.edu.au.
Source: Cell death & disease [Cell Death Dis] 2025 Nov 03; Vol. 16 (1), pp. 778. Date of Electronic Publication: 2025 Nov 03.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-4889
DOI:10.1038/s41419-025-08094-x