OSU-ERβ-12: a promising pre-clinical candidate selective estrogen receptor beta agonist.

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Title: OSU-ERβ-12: a promising pre-clinical candidate selective estrogen receptor beta agonist.
Authors: Young GM; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, 496 W. 12th Ave, Columbus, OH, 43210, USA., Helms TH; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, 496 W. 12th Ave, Columbus, OH, 43210, USA., Kulp SK; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, 496 W. 12th Ave, Columbus, OH, 43210, USA., Adeluola AA; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, 496 W. 12th Ave, Columbus, OH, 43210, USA., Radomska HS; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, 496 W. 12th Ave, Columbus, OH, 43210, USA., Wilson TA; Drug Discovery Shared Resource, Comprehensive Cancer Center, The Ohio State University, 496 W. 12th Ave, Columbus, OH, 43210, USA., Shakya R; Preclinical Therapeutics Mouse Modeling, Comprehensive Cancer Center, The Ohio State University, 496 W. 12th Ave, Columbus, OH, 43210, USA., Kabat A; Charles River Labs, 1 Innovation , 01605, Worcester, MA, USA., Mulcahy G; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, 496 W. 12th Ave, Columbus, OH, 43210, USA., Mayo AK; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, 496 W. 12th Ave, Columbus, OH, 43210, USA., Malbrue RA; Department of Veterinary Preventative Medicine, College of Veterinary Medicine, The Ohio State University, 1900 Coffey Road , OH, Columbus, 43210, USA., Kisseberth WC; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon L Tharp St, Ohio, 43210, USA., Bennett CE; Drug Discovery Shared Resource, Comprehensive Cancer Center, The Ohio State University, 496 W. 12th Ave, Columbus, OH, 43210, USA.; Drug Development Institute, Comprehensive Cancer Center, The Ohio State University, 410 W. 12th Ave, Columbus, OH, 43210, USA., Coss CC; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, 496 W. 12th Ave, Columbus, OH, 43210, USA. coss.16@osu.edu.; Drug Development Institute, Comprehensive Cancer Center, The Ohio State University, 410 W. 12th Ave, Columbus, OH, 43210, USA. coss.16@osu.edu.
Source: Scientific reports [Sci Rep] 2025 Nov 03; Vol. 15 (1), pp. 38377. Date of Electronic Publication: 2025 Nov 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2045-2322
DOI:10.1038/s41598-025-22258-x