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Genome edited intestine liver on a chip system for integrated intestinal hepatic drug absorption and metabolism evaluation.

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Title: Genome edited intestine liver on a chip system for integrated intestinal hepatic drug absorption and metabolism evaluation.
Authors: Negoro R; Laboratory of Molecular Pharmacokinetics, College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-Higashi, Kusatsu, 525-8577, Japan. negoro-r@fc.ritsumei.ac.jp., Deguchi S; Department of Synthetic Human Body System, Medical Research Institute, Institute of Integrated Research, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan., Yamazaki D; Division of Pharmacology, Center for Biological Safety and Research, National Institute of Health Sciences, 3-25-26 Tono-machi, Kawasaki-ku, Kawasaki, 210-9501, Japan., Takayama K; Department of Synthetic Human Body System, Medical Research Institute, Institute of Integrated Research, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan., Fujita T; Laboratory of Molecular Pharmacokinetics, College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-Higashi, Kusatsu, 525-8577, Japan.
Source: Scientific reports [Sci Rep] 2025 Nov 04; Vol. 15 (1), pp. 38609. Date of Electronic Publication: 2025 Nov 04.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Negoro+R%22">Negoro R</searchLink>; Laboratory of Molecular Pharmacokinetics, College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-Higashi, Kusatsu, 525-8577, Japan. negoro-r@fc.ritsumei.ac.jp.<br /><searchLink fieldCode="AU" term="%22Deguchi+S%22">Deguchi S</searchLink>; Department of Synthetic Human Body System, Medical Research Institute, Institute of Integrated Research, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan.<br /><searchLink fieldCode="AU" term="%22Yamazaki+D%22">Yamazaki D</searchLink>; Division of Pharmacology, Center for Biological Safety and Research, National Institute of Health Sciences, 3-25-26 Tono-machi, Kawasaki-ku, Kawasaki, 210-9501, Japan.<br /><searchLink fieldCode="AU" term="%22Takayama+K%22">Takayama K</searchLink>; Department of Synthetic Human Body System, Medical Research Institute, Institute of Integrated Research, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan.<br /><searchLink fieldCode="AU" term="%22Fujita+T%22">Fujita T</searchLink>; Laboratory of Molecular Pharmacokinetics, College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-Higashi, Kusatsu, 525-8577, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2025 Nov 04; Vol. 15 (1), pp. 38609. <i>Date of Electronic Publication: </i>2025 Nov 04.
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