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Non-selective beta-blockers enhance resolution of induced infections in animals and healthcare-associated infections in humans.

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Title: Non-selective beta-blockers enhance resolution of induced infections in animals and healthcare-associated infections in humans.
Authors: Occhinegro A; Department of Biomedical and Neuromotor Sciences (DIBINEM) Physiology Unit, University of Bologna, Piazza DiPorta S. Donato 2, 40126, Bologna, Italy.; Preclinical Critical Care Unit, Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia., Ventrella D; Department of Veterinary Medical Sciences (DIMEVET), University of Bologna, Ozzano Dell'Emilia (BO), Italy., Rosa S; Department of Biomedical and Neuromotor Sciences (DIBINEM) Physiology Unit, University of Bologna, Piazza DiPorta S. Donato 2, 40126, Bologna, Italy., Alberti L; Department of Biomedical and Neuromotor Sciences (DIBINEM) Physiology Unit, University of Bologna, Piazza DiPorta S. Donato 2, 40126, Bologna, Italy., Amici R; Department of Biomedical and Neuromotor Sciences (DIBINEM) Physiology Unit, University of Bologna, Piazza DiPorta S. Donato 2, 40126, Bologna, Italy., Cerri M; Department of Biomedical and Neuromotor Sciences (DIBINEM) Physiology Unit, University of Bologna, Piazza DiPorta S. Donato 2, 40126, Bologna, Italy., Hitrec T; Department of Biomedical and Neuromotor Sciences (DIBINEM) Physiology Unit, University of Bologna, Piazza DiPorta S. Donato 2, 40126, Bologna, Italy., Tupone D; Department of Biomedical and Neuromotor Sciences (DIBINEM) Physiology Unit, University of Bologna, Piazza DiPorta S. Donato 2, 40126, Bologna, Italy.; Department of Neurological Surgery, Oregon Health & Science University, Portland, OR, USA., Cappellini A; Department of Biomedical and Neuromotor Sciences (DIBINEM) Physiology Unit, University of Bologna, Piazza DiPorta S. Donato 2, 40126, Bologna, Italy., Ratti S; Department of Biomedical and Neuromotor Sciences (DIBINEM) Physiology Unit, University of Bologna, Piazza DiPorta S. Donato 2, 40126, Bologna, Italy., Elmi A; Department of Veterinary Medical Sciences (DIMEVET), University of Bologna, Ozzano Dell'Emilia (BO), Italy.; Department of Veterinary Sciences (DSV), University of Pisa, 56124, Pisa (PI), Italy., Zannoni A; Department of Veterinary Medical Sciences (DIMEVET), University of Bologna, Ozzano Dell'Emilia (BO), Italy., Felici S; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy., Golinelli D; Health Services Research, Evaluation and Policy Unit, Local Health Authority of Romagna, Ravenna, Italy., Luppi M; Department of Biomedical and Neuromotor Sciences (DIBINEM) Physiology Unit, University of Bologna, Piazza DiPorta S. Donato 2, 40126, Bologna, Italy., Lankadeva YR; Preclinical Critical Care Unit, Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia.; Department of Critical Care, Melbourne Medical School, University of Melbourne, Parkville, VIC, Australia., May CN; Preclinical Critical Care Unit, Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia.; Department of Critical Care, Melbourne Medical School, University of Melbourne, Parkville, VIC, Australia., McAllen RM; Preclinical Critical Care Unit, Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia., McKinley MJ; Preclinical Critical Care Unit, Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia.; Department of Anatomy and Physiology, University of Melbourne, Parkville, VIC, Australia., Passaglia P; Department of Oral and Basic Biology Ribeirão Preto, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil., Piscitiello E; Department of Biomedical and Neuromotor Sciences (DIBINEM) Physiology Unit, University of Bologna, Piazza DiPorta S. Donato 2, 40126, Bologna, Italy., Taddei L; Department of Biomedical and Neuromotor Sciences (DIBINEM) Physiology Unit, University of Bologna, Piazza DiPorta S. Donato 2, 40126, Bologna, Italy., Giannella M; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.; Infectious Diseases Unit, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy., Viale P; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.; Infectious Diseases Unit, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy., Bacci ML; Department of Veterinary Medical Sciences (DIMEVET), University of Bologna, Ozzano Dell'Emilia (BO), Italy., Rucci P; Department of Biomedical and Neuromotor Sciences (DIBINEM) Physiology Unit, University of Bologna, Piazza DiPorta S. Donato 2, 40126, Bologna, Italy., Lazzarotto T; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy.; Microbiology Unit, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy., Martelli D; Department of Biomedical and Neuromotor Sciences (DIBINEM) Physiology Unit, University of Bologna, Piazza DiPorta S. Donato 2, 40126, Bologna, Italy. d.martelli@unibo.it.; Centre for Applied Biomedical Research (CRBA), University of Bologna, Bologna, Italy. d.martelli@unibo.it.
Source: Scientific reports [Sci Rep] 2025 Nov 05; Vol. 15 (1), pp. 38766. Date of Electronic Publication: 2025 Nov 05.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2045-2322
DOI:10.1038/s41598-025-22723-7