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Bempedoic Acid mitigates BCG-induced depression in mice by modulating TNF-α/NF-κB signaling and restoring brain serotonin contents.

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Title: Bempedoic Acid mitigates BCG-induced depression in mice by modulating TNF-α/NF-κB signaling and restoring brain serotonin contents.
Authors: Tarwani RS; School of Pharmacy & Technology Management, SVKM NMIMS Global University, Dhule 424001 Maharashtra, India., Awathale SN; School of Pharmacy & Technology Management, SVKM NMIMS Global University, Dhule 424001 Maharashtra, India., Goyal SN; School of Pharmacy & Technology Management, SVKM NMIMS Global University, Dhule 424001 Maharashtra, India., Sherikar AK; School of Pharmacy & Technology Management, SVKM NMIMS Global University, Dhule 424001 Maharashtra, India., Bawane PP; School of Pharmacy & Technology Management, SVKM NMIMS Global University, Dhule 424001 Maharashtra, India. Electronic address: pradip.bawane@svkm.ac.in., Nakhate KT; School of Pharmacy & Technology Management, SVKM NMIMS Global University, Dhule 424001 Maharashtra, India. Electronic address: kartik.nakhate@svkm.ac.in.
Source: Brain research [Brain Res] 2025 Dec 15; Vol. 1869, pp. 150031. Date of Electronic Publication: 2025 Nov 04.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 0045503 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6240 (Electronic) Linking ISSN: 00068993 NLM ISO Abbreviation: Brain Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1872-6240
DOI:10.1016/j.brainres.2025.150031