Carafe enables high quality in silico spectral library generation for data-independent acquisition proteomics.

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Title: Carafe enables high quality in silico spectral library generation for data-independent acquisition proteomics.
Authors: Wen B; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Hsu C; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Shteynberg D; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Zeng WF; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany., Riffle M; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Chang A; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Mudge MC; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Nunn BL; Department of Genome Sciences, University of Washington, Seattle, WA, USA., MacLean BX; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Berg MD; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Villén J; Department of Genome Sciences, University of Washington, Seattle, WA, USA., MacCoss MJ; Department of Genome Sciences, University of Washington, Seattle, WA, USA. maccoss@uw.edu., Noble WS; Department of Genome Sciences, University of Washington, Seattle, WA, USA. wnoble@uw.edu.; Paul G. Allen School of Computer Science and Engineering, University of Washington, Seattle, WA, USA. wnoble@uw.edu.
Source: Nature communications [Nat Commun] 2025 Nov 06; Vol. 16 (1), pp. 9815. Date of Electronic Publication: 2025 Nov 06.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-64928-4