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Isoquercitrin Improves Insulin Resistance by Inhibiting PTP1B-Regulated IRS/PI3K/AKT Signaling Pathway.

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Title: Isoquercitrin Improves Insulin Resistance by Inhibiting PTP1B-Regulated IRS/PI3K/AKT Signaling Pathway.
Authors: Liu SY; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.; School of Pharmacy, Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.; Department of Pharmacy, Heilongjiang Provincial Hospital, Harbin, 150000, China., Yu LJ; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.; School of Pharmacy, Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China., Zhang SN; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China., Yue JK; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China., Jiang GJ; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China., Lu SH; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.; School of Pharmacy, Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China., Li YJ; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.; School of Pharmacy, Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China., Meng JY; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.; School of Pharmacy, Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China., Huang GH; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China. Guihonghuang666@163.com.; Guangxi Health Commission Key Laboratory of Glucose and Lipid Metabolism Disorders; Key Laboratory of Diabetic Systems Medicine, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China. Guihonghuang666@163.com.; Guangxi Key Laboratory of Drug Discovery and Optimization; Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China. Guihonghuang666@163.com.
Source: Chinese journal of integrative medicine [Chin J Integr Med] 2026 Apr; Vol. 32 (4), pp. 340-349. Date of Electronic Publication: 2025 Nov 07.
Publication Type: Journal Article
Journal Info: Publisher: Chinese Journal of Integrated Traditional and Western Medicine Press Country of Publication: China NLM ID: 101181180 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1993-0402 (Electronic) Linking ISSN: 16720415 NLM ISO Abbreviation: Chin J Integr Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1993-0402
DOI:10.1007/s11655-025-3934-6