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Isoquercitrin Improves Insulin Resistance by Inhibiting PTP1B-Regulated IRS/PI3K/AKT Signaling Pathway.

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Title: Isoquercitrin Improves Insulin Resistance by Inhibiting PTP1B-Regulated IRS/PI3K/AKT Signaling Pathway.
Authors: Liu SY; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.; School of Pharmacy, Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.; Department of Pharmacy, Heilongjiang Provincial Hospital, Harbin, 150000, China., Yu LJ; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.; School of Pharmacy, Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China., Zhang SN; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China., Yue JK; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China., Jiang GJ; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China., Lu SH; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.; School of Pharmacy, Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China., Li YJ; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.; School of Pharmacy, Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China., Meng JY; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.; School of Pharmacy, Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China., Huang GH; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China. Guihonghuang666@163.com.; Guangxi Health Commission Key Laboratory of Glucose and Lipid Metabolism Disorders; Key Laboratory of Diabetic Systems Medicine, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China. Guihonghuang666@163.com.; Guangxi Key Laboratory of Drug Discovery and Optimization; Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China. Guihonghuang666@163.com.
Source: Chinese journal of integrative medicine [Chin J Integr Med] 2026 Apr; Vol. 32 (4), pp. 340-349. Date of Electronic Publication: 2025 Nov 07.
Publication Type: Journal Article
Journal Info: Publisher: Chinese Journal of Integrated Traditional and Western Medicine Press Country of Publication: China NLM ID: 101181180 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1993-0402 (Electronic) Linking ISSN: 16720415 NLM ISO Abbreviation: Chin J Integr Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Isoquercitrin Improves Insulin Resistance by Inhibiting PTP1B-Regulated IRS/PI3K/AKT Signaling Pathway.
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  Data: <searchLink fieldCode="AU" term="%22Liu+SY%22">Liu SY</searchLink>; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.; School of Pharmacy, Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.; Department of Pharmacy, Heilongjiang Provincial Hospital, Harbin, 150000, China.<br /><searchLink fieldCode="AU" term="%22Yu+LJ%22">Yu LJ</searchLink>; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.; School of Pharmacy, Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.<br /><searchLink fieldCode="AU" term="%22Zhang+SN%22">Zhang SN</searchLink>; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.<br /><searchLink fieldCode="AU" term="%22Yue+JK%22">Yue JK</searchLink>; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.<br /><searchLink fieldCode="AU" term="%22Jiang+GJ%22">Jiang GJ</searchLink>; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.<br /><searchLink fieldCode="AU" term="%22Lu+SH%22">Lu SH</searchLink>; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.; School of Pharmacy, Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.<br /><searchLink fieldCode="AU" term="%22Li+YJ%22">Li YJ</searchLink>; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.; School of Pharmacy, Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.<br /><searchLink fieldCode="AU" term="%22Meng+JY%22">Meng JY</searchLink>; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.; School of Pharmacy, Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China.<br /><searchLink fieldCode="AU" term="%22Huang+GH%22">Huang GH</searchLink>; Department of Pharmacy, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China. Guihonghuang666@163.com.; Guangxi Health Commission Key Laboratory of Glucose and Lipid Metabolism Disorders; Key Laboratory of Diabetic Systems Medicine, the Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China. Guihonghuang666@163.com.; Guangxi Key Laboratory of Drug Discovery and Optimization; Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, 541199, China. Guihonghuang666@163.com.
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  Data: <searchLink fieldCode="JN" term="%22101181180%22">Chinese journal of integrative medicine</searchLink> [Chin J Integr Med] 2026 Apr; Vol. 32 (4), pp. 340-349. <i>Date of Electronic Publication: </i>2025 Nov 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Chinese+Journal+of+Integrated+Traditional+and+Western+Medicine+Press%22">Chinese Journal of Integrated Traditional and Western Medicine Press </searchLink><i>Country of Publication: </i>China <i>NLM ID: </i>101181180 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1993-0402 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216720415%22">16720415 </searchLink><i>NLM ISO Abbreviation: </i>Chin J Integr Med <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1007/s11655-025-3934-6
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      – Code: eng
        Text: English
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        StartPage: 340
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      – TitleFull: Isoquercitrin Improves Insulin Resistance by Inhibiting PTP1B-Regulated IRS/PI3K/AKT Signaling Pathway.
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            NameFull: Liu SY
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            NameFull: Yu LJ
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            – D: 01
              M: 04
              Text: 2026 Apr
              Type: published
              Y: 2026
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              Value: 1993-0402
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              Value: 32
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            – TitleFull: Chinese journal of integrative medicine
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