Targeting the cGAS-STING Pathway for Cancer Immunotherapy: From Small-Molecule Agonists to Advanced Nanomaterials.

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Title: Targeting the cGAS-STING Pathway for Cancer Immunotherapy: From Small-Molecule Agonists to Advanced Nanomaterials.
Authors: Guo Z; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China., Liu T; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China., Gao Q; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China., Wang C; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China., Wang Q; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China., Du R; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China., Liu Y; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China., Li H; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China., Huang Y; College of Nursing and Health Management, Wuhan Donghu College, Wuhan 430212, P. R. China., Liu Y; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China.; Key Laboratory of Catalysis and Energy Materials Chemistry (Ministry of Education) & Hubei Key Laboratory of Catalysis and Materials Science, South-Central Minzu University, Wuhan 430074, P. R. China., Liu Y; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China.
Source: Molecular pharmaceutics [Mol Pharm] 2025 Dec 01; Vol. 22 (12), pp. 7262-7284. Date of Electronic Publication: 2025 Nov 07.
Publication Type: Journal Article; Review
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-8392 (Electronic) Linking ISSN: 15438384 NLM ISO Abbreviation: Mol Pharm Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1543-8392
DOI:10.1021/acs.molpharmaceut.5c01263