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Targeting the cGAS-STING Pathway for Cancer Immunotherapy: From Small-Molecule Agonists to Advanced Nanomaterials.

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Title: Targeting the cGAS-STING Pathway for Cancer Immunotherapy: From Small-Molecule Agonists to Advanced Nanomaterials.
Authors: Guo Z; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China., Liu T; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China., Gao Q; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China., Wang C; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China., Wang Q; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China., Du R; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China., Liu Y; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China., Li H; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China., Huang Y; College of Nursing and Health Management, Wuhan Donghu College, Wuhan 430212, P. R. China., Liu Y; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China.; Key Laboratory of Catalysis and Energy Materials Chemistry (Ministry of Education) & Hubei Key Laboratory of Catalysis and Materials Science, South-Central Minzu University, Wuhan 430074, P. R. China., Liu Y; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China.
Source: Molecular pharmaceutics [Mol Pharm] 2025 Dec 01; Vol. 22 (12), pp. 7262-7284. Date of Electronic Publication: 2025 Nov 07.
Publication Type: Journal Article; Review
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-8392 (Electronic) Linking ISSN: 15438384 NLM ISO Abbreviation: Mol Pharm Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting the cGAS-STING Pathway for Cancer Immunotherapy: From Small-Molecule Agonists to Advanced Nanomaterials.
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  Data: <searchLink fieldCode="AU" term="%22Guo+Z%22">Guo Z</searchLink>; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China.<br /><searchLink fieldCode="AU" term="%22Liu+T%22">Liu T</searchLink>; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China.<br /><searchLink fieldCode="AU" term="%22Gao+Q%22">Gao Q</searchLink>; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China.<br /><searchLink fieldCode="AU" term="%22Du+R%22">Du R</searchLink>; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; College of Nursing and Health Management, Wuhan Donghu College, Wuhan 430212, P. R. China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China.; Key Laboratory of Catalysis and Energy Materials Chemistry (Ministry of Education) & Hubei Key Laboratory of Catalysis and Materials Science, South-Central Minzu University, Wuhan 430074, P. R. China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; State Key Laboratory of Advanced Separation Membrane Materials, School of Chemistry & School of Chemical Engineering and Technology & School of Material Science and Engineering, Tiangong University, Tianjin 300387, P. R. China.
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  Data: <searchLink fieldCode="JN" term="%22101197791%22">Molecular pharmaceutics</searchLink> [Mol Pharm] 2025 Dec 01; Vol. 22 (12), pp. 7262-7284. <i>Date of Electronic Publication: </i>2025 Nov 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101197791 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1543-8392 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215438384%22">15438384 </searchLink><i>NLM ISO Abbreviation: </i>Mol Pharm <i>Subsets: </i>MEDLINE
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        Value: 10.1021/acs.molpharmaceut.5c01263
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            – D: 01
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              Text: 2025 Dec 01
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