6-PPD induces mitochondrial dysfunction and reduces healthspan and lifespan through SKN-1 in Caenorhabditis elegans.

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Title: 6-PPD induces mitochondrial dysfunction and reduces healthspan and lifespan through SKN-1 in Caenorhabditis elegans.
Authors: Hyun M; Division of Gyeongnam Bio-Environmental Research, Bio-Health Research Center, Jinju 52834, Republic of Korea. Electronic address: moonjung.hyun@kitox.re.kr., Rathor L; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA., Kim HJ; Division of Gyeongnam Bio-Environmental Research, Bio-Health Research Center, Jinju 52834, Republic of Korea., Lee HJ; Division of Gyeongnam Bio-Environmental Research, Bio-Health Research Center, Jinju 52834, Republic of Korea., McElroy T; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA., Ji M; College of Pharmacy, Sunchon National University, Suncheon 57922, Republic of Korea., Choi MS; Department of Environmental Engineering, Jeonbuk National University, Jeonju 54896, Republic of Korea., Beck S; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA., Bailey J; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA., Kim HH; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA; College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea., Sheng Y; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA., Heo JD; Division of Gyeongnam Bio-Environmental Research, Bio-Health Research Center, Jinju 52834, Republic of Korea., Wohlgemuth S; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA., Xiao R; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA., Kim GS; College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea., Paik MJ; College of Pharmacy, Sunchon National University, Suncheon 57922, Republic of Korea., Kim YH; Department of Environmental Engineering, Jeonbuk National University, Jeonju 54896, Republic of Korea., Kim SH; Division of Jeonbuk Advanced Bio Research, Korea Institute of Toxicology, Jeongeup 56212, Republic of Korea., Lee MH; Department of Internal Medicine, Hematology/Oncology Division, Brody School of Medicine at East Carolina University, Greenville, NC 27834, USA; Department of Biology, East Carolina University, Greenville, NC 27858, USA. Electronic address: leemy@ecu.edu., Han SM; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA. Electronic address: han.s@ufl.edu.
Source: Journal of hazardous materials [J Hazard Mater] 2025 Dec 05; Vol. 500, pp. 140332. Date of Electronic Publication: 2025 Oct 31.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9422688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3336 (Electronic) Linking ISSN: 03043894 NLM ISO Abbreviation: J Hazard Mater Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-3336
DOI:10.1016/j.jhazmat.2025.140332