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6-PPD induces mitochondrial dysfunction and reduces healthspan and lifespan through SKN-1 in Caenorhabditis elegans.

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Title: 6-PPD induces mitochondrial dysfunction and reduces healthspan and lifespan through SKN-1 in Caenorhabditis elegans.
Authors: Hyun M; Division of Gyeongnam Bio-Environmental Research, Bio-Health Research Center, Jinju 52834, Republic of Korea. Electronic address: moonjung.hyun@kitox.re.kr., Rathor L; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA., Kim HJ; Division of Gyeongnam Bio-Environmental Research, Bio-Health Research Center, Jinju 52834, Republic of Korea., Lee HJ; Division of Gyeongnam Bio-Environmental Research, Bio-Health Research Center, Jinju 52834, Republic of Korea., McElroy T; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA., Ji M; College of Pharmacy, Sunchon National University, Suncheon 57922, Republic of Korea., Choi MS; Department of Environmental Engineering, Jeonbuk National University, Jeonju 54896, Republic of Korea., Beck S; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA., Bailey J; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA., Kim HH; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA; College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea., Sheng Y; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA., Heo JD; Division of Gyeongnam Bio-Environmental Research, Bio-Health Research Center, Jinju 52834, Republic of Korea., Wohlgemuth S; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA., Xiao R; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA., Kim GS; College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea., Paik MJ; College of Pharmacy, Sunchon National University, Suncheon 57922, Republic of Korea., Kim YH; Department of Environmental Engineering, Jeonbuk National University, Jeonju 54896, Republic of Korea., Kim SH; Division of Jeonbuk Advanced Bio Research, Korea Institute of Toxicology, Jeongeup 56212, Republic of Korea., Lee MH; Department of Internal Medicine, Hematology/Oncology Division, Brody School of Medicine at East Carolina University, Greenville, NC 27834, USA; Department of Biology, East Carolina University, Greenville, NC 27858, USA. Electronic address: leemy@ecu.edu., Han SM; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA. Electronic address: han.s@ufl.edu.
Source: Journal of hazardous materials [J Hazard Mater] 2025 Dec 05; Vol. 500, pp. 140332. Date of Electronic Publication: 2025 Oct 31.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9422688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3336 (Electronic) Linking ISSN: 03043894 NLM ISO Abbreviation: J Hazard Mater Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: 6-PPD induces mitochondrial dysfunction and reduces healthspan and lifespan through SKN-1 in Caenorhabditis elegans.
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  Data: <searchLink fieldCode="AU" term="%22Hyun+M%22">Hyun M</searchLink>; Division of Gyeongnam Bio-Environmental Research, Bio-Health Research Center, Jinju 52834, Republic of Korea. Electronic address: moonjung.hyun@kitox.re.kr.<br /><searchLink fieldCode="AU" term="%22Rathor+L%22">Rathor L</searchLink>; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA.<br /><searchLink fieldCode="AU" term="%22Kim+HJ%22">Kim HJ</searchLink>; Division of Gyeongnam Bio-Environmental Research, Bio-Health Research Center, Jinju 52834, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+HJ%22">Lee HJ</searchLink>; Division of Gyeongnam Bio-Environmental Research, Bio-Health Research Center, Jinju 52834, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22McElroy+T%22">McElroy T</searchLink>; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA.<br /><searchLink fieldCode="AU" term="%22Ji+M%22">Ji M</searchLink>; College of Pharmacy, Sunchon National University, Suncheon 57922, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+MS%22">Choi MS</searchLink>; Department of Environmental Engineering, Jeonbuk National University, Jeonju 54896, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Beck+S%22">Beck S</searchLink>; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA.<br /><searchLink fieldCode="AU" term="%22Bailey+J%22">Bailey J</searchLink>; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA.<br /><searchLink fieldCode="AU" term="%22Kim+HH%22">Kim HH</searchLink>; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA; College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Sheng+Y%22">Sheng Y</searchLink>; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA.<br /><searchLink fieldCode="AU" term="%22Heo+JD%22">Heo JD</searchLink>; Division of Gyeongnam Bio-Environmental Research, Bio-Health Research Center, Jinju 52834, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Wohlgemuth+S%22">Wohlgemuth S</searchLink>; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA.<br /><searchLink fieldCode="AU" term="%22Xiao+R%22">Xiao R</searchLink>; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA.<br /><searchLink fieldCode="AU" term="%22Kim+GS%22">Kim GS</searchLink>; College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Paik+MJ%22">Paik MJ</searchLink>; College of Pharmacy, Sunchon National University, Suncheon 57922, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+YH%22">Kim YH</searchLink>; Department of Environmental Engineering, Jeonbuk National University, Jeonju 54896, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SH%22">Kim SH</searchLink>; Division of Jeonbuk Advanced Bio Research, Korea Institute of Toxicology, Jeongeup 56212, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+MH%22">Lee MH</searchLink>; Department of Internal Medicine, Hematology/Oncology Division, Brody School of Medicine at East Carolina University, Greenville, NC 27834, USA; Department of Biology, East Carolina University, Greenville, NC 27858, USA. Electronic address: leemy@ecu.edu.<br /><searchLink fieldCode="AU" term="%22Han+SM%22">Han SM</searchLink>; Department of Physiology and Aging, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32610, USA. Electronic address: han.s@ufl.edu.
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  Data: <searchLink fieldCode="JN" term="%229422688%22">Journal of hazardous materials</searchLink> [J Hazard Mater] 2025 Dec 05; Vol. 500, pp. 140332. <i>Date of Electronic Publication: </i>2025 Oct 31.
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