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Black ginseng extract alleviates particulate matter-induced airway inflammation by suppressing the ROS/NLRP3/caspase-1 pathway in macrophages.

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Title: Black ginseng extract alleviates particulate matter-induced airway inflammation by suppressing the ROS/NLRP3/caspase-1 pathway in macrophages.
Authors: Song YN; Natural Product Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 30 Yeongudanji-ro, Cheongju, 28116, Republic of Korea; Department of Biological Sciences, College of Bioscience and Biotechnology, Chungnam National University, Daejeon, 34134, Republic of Korea., Kim SH; DJU Industry-University Cooperation Foundation, Daejeon University, Daejeon, 34520, Republic of Korea., Ro H; Department of Biological Sciences, College of Bioscience and Biotechnology, Chungnam National University, Daejeon, 34134, Republic of Korea., Yun SH; Natural Product Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 30 Yeongudanji-ro, Cheongju, 28116, Republic of Korea; Department of Anatomy & Cell Biology, Department of Medical Science, College of Medicine, Chungnam National University, 266, Munhwa-Ro, Daejeon, 35015, Republic of Korea., Oh ES; Natural Product Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 30 Yeongudanji-ro, Cheongju, 28116, Republic of Korea., Kim DY; Natural Product Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 30 Yeongudanji-ro, Cheongju, 28116, Republic of Korea., Ryu HW; Natural Product Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 30 Yeongudanji-ro, Cheongju, 28116, Republic of Korea., Hong ST; Department of Anatomy & Cell Biology, Department of Medical Science, College of Medicine, Chungnam National University, 266, Munhwa-Ro, Daejeon, 35015, Republic of Korea. Electronic address: mogwai@cnu.ac.kr., Lee DY; BK21 FOUR KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu, 41566, Republic of Korea. Electronic address: dylee80@knu.ac.kr., Lee SU; Natural Product Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 30 Yeongudanji-ro, Cheongju, 28116, Republic of Korea. Electronic address: iamsuui@kribb.re.kr.
Source: Journal of ethnopharmacology [J Ethnopharmacol] 2026 Feb 28; Vol. 357, pp. 120872. Date of Electronic Publication: 2025 Nov 06.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1872-7573
DOI:10.1016/j.jep.2025.120872