Early alpha-synuclein accumulation, oxidative stress and inflammation in the proximal colon of c-rel-/- mouse model of Parkinson's disease.

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Title: Early alpha-synuclein accumulation, oxidative stress and inflammation in the proximal colon of c-rel-/- mouse model of Parkinson's disease.
Authors: Parrella E; Department of Molecular and Translational Medicine, Division of Pharmacology, University of Brescia, Italy; Departmental Faculty of Medicine, Saint Camillus International University of Health Sciences, Rome, Italy; Section of Innovation Biomedicine, Department of Engineering for Innovation Medicine, University of Verona, Verona, Italy. Electronic address: edoardo.parrella@univr.it., Gennari MM; Department of Molecular and Translational Medicine, Division of Pharmacology, University of Brescia, Italy. Electronic address: michele.gennari@unibs.it., Abate G; Department of Molecular and Translational Medicine, Division of Pharmacology, University of Brescia, Italy. Electronic address: giulia.abate@unibs.it., Pucci M; Department of Molecular and Translational Medicine, Division of Pharmacology, University of Brescia, Italy. Electronic address: mariachiara.pucci@unibs.it., Schioppa T; Department of Molecular and Translational Medicine, Division of Experimental Oncology and Immunology, University of Brescia, Brescia, Italy. Electronic address: tiziana.schioppa@unicamillus.org., Bosisio D; Department of Molecular and Translational Medicine, Division of Experimental Oncology and Immunology, University of Brescia, Brescia, Italy. Electronic address: daniela.bosisio@unibs.it., Tirelli E; Department of Molecular and Translational Medicine, Division of Pharmacology, University of Brescia, Italy. Electronic address: e.tirelli004@unibs.it., Benarese M; Department of Molecular and Translational Medicine, Division of Pharmacology, University of Brescia, Italy. Electronic address: marina.benarese@unibs.it., Vegezzi G; Department of Molecular and Translational Medicine, Division of Pharmacology, University of Brescia, Italy. Electronic address: gaia.vegezzi@libero.it., Silletti MG; Department of Molecular and Translational Medicine, Division of Pharmacology, University of Brescia, Italy. Electronic address: mariagrazia.silletti@studenti.univr.it., Fritzsch C; Department of Molecular and Translational Medicine, Division of Pharmacology, University of Brescia, Italy. Electronic address: chiara.fritzsch@unibs.it., Uberti D; Department of Molecular and Translational Medicine, Division of Pharmacology, University of Brescia, Italy. Electronic address: daniela.uberti@unibs.it., Pizzi M; Department of Molecular and Translational Medicine, Division of Pharmacology, University of Brescia, Italy. Electronic address: marina.pizzi@unibs.it., Porrini V; Department of Molecular and Translational Medicine, Division of Pharmacology, University of Brescia, Italy. Electronic address: vanessa.porrini@unibs.it.
Source: Neurobiology of disease [Neurobiol Dis] 2025 Dec; Vol. 217, pp. 107182. Date of Electronic Publication: 2025 Nov 07.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1095-953X
DOI:10.1016/j.nbd.2025.107182