Molecular hydrogen mitigates acetaminophen-induced liver injury and enhances the effects of N-acetylcysteine in diabetic mice.

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Title: Molecular hydrogen mitigates acetaminophen-induced liver injury and enhances the effects of N-acetylcysteine in diabetic mice.
Authors: Kamimura N; Laboratory for Clinical Research, Collaborative Research Center, Nippon Medical School, Tokyo, Japan; Department of Biochemistry and Cell Biology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan. Electronic address: nanakash@nms.ac.jp., Iuchi K; Department of Biochemistry and Cell Biology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan; Frontier Research Institute for Interdisciplinary Sciences (FRIS), Tohoku University, Sendai, Japan; Core Facility Center, Organization for the Promotion and Support of Research Activities Tohoku University, Sendai, Japan., Igarashi T; Department of Ophthalmology, Nippon Medical School Chiba Hokusoh Hospital, Chiba, Japan; Department of Biochemistry and Molecular Biology, Nippon Medical School, Tokyo, Japan; Division of Molecular and Medical Genetics, Center for Gene and Cell Therapy, Institute of Medical Science, University of Tokyo, Tokyo, Japan., Ohsawa I; Biological Process of Aging, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan., Nito C; Laboratory for Clinical Research, Collaborative Research Center, Nippon Medical School, Tokyo, Japan., Usuda J; Laboratory for Clinical Research, Collaborative Research Center, Nippon Medical School, Tokyo, Japan; Department of Thoracic Surgery, Nippon Medical School, Tokyo, Japan., Ohta S; Department of Biochemistry and Cell Biology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan; Department of Neurology Medicine, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Source: The Journal of nutritional biochemistry [J Nutr Biochem] 2026 Mar; Vol. 149, pp. 110176. Date of Electronic Publication: 2025 Nov 07.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 9010081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4847 (Electronic) Linking ISSN: 09552863 NLM ISO Abbreviation: J Nutr Biochem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-4847
DOI:10.1016/j.jnutbio.2025.110176