Evaluation of Interventions for Cognitive Symptoms in Long COVID: A Randomized Clinical Trial.

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Title: Evaluation of Interventions for Cognitive Symptoms in Long COVID: A Randomized Clinical Trial.
Authors: Knopman DS; Department of Neurology, Mayo Clinic, Rochester, Minnesota., Koltai D; Department of Neurology, Duke University School of Medicine, Durham, North Carolina., Laskowitz DT; Department of Neurology, Duke University School of Medicine, Durham, North Carolina., Becker J; Division of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, New York., Charvet L; Department of Neurology, Grossman School of Medicine, New York University, New York., Wisnivesky J; Division of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, New York., Federman A; Division of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, New York., Silverstein A; Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina., Lokhnygina Y; Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina.; Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina., Pilloni G; Department of Neurology, Grossman School of Medicine, New York University, New York., Haddad M; Department of Rehabilitation Medicine, Emory University School of Medicine, Atlanta, Georgia., Mahncke H; Posit Science, San Francisco, California., Van Vleet T; Posit Science, San Francisco, California., Huang R; Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina., Cox W; RECOVER Patient, Caregiver, or Community Representative, Durham, North Carolina., Terry D; RECOVER Patient, Caregiver, or Community Representative, Durham, North Carolina., Karwowski J; RECOVER Patient, Caregiver, or Community Representative, Durham, North Carolina., McCray N; RECOVER Patient, Caregiver, or Community Representative, Durham, North Carolina., Lin JJ; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York., McComsey GA; Department of Medicine and Pediatrics, Case Western Reserve University and University Hospitals Cleveland Medical Center, Cleveland, Ohio., Singh U; Department of Internal Medicine, University of Iowa, Iowa City., Geng LN; Department of Medicine, Stanford University School of Medicine, Stanford, California., Chu HY; Department of Medicine, University of Washington, Seattle., Reece R; Department of Medicine, West Virginia University School of Medicine, Morgantown., Moy J; Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois., Arvanitakis Z; Department of Neurological Sciences, Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois., Parthasarathy S; Department of Medicine, University of Arizona, Tucson., Patterson TF; Department of Medicine/Infectious Diseases, University of Texas Health San Antonio, San Antonio., Gupta A; Departments of Internal Medicine and Neurology, University of Kansas Medical Center, Kansas City., Ostrosky-Zeichner L; Division of Infectious Diseases, University of Texas Health Science Center at Houston, Houston., Parsonnet J; Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire., Kiriakopoulos ET; Department of Neurology, Dartmouth Health, Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire., Fong TG; Department of Neurology, Beth Israel Deaconess Medical Center and Harvard School of Medicine, Boston, Massachusetts., Mullington J; Department of Neurology, Beth Israel Deaconess Medical Center and Harvard School of Medicine, Boston, Massachusetts., Jolley S; Division of Pulmonary and Critical Care Medicine, University of Colorado Anschutz Medical Center, Aurora., Shah NS; Division of Infectious Diseases, Endeavor Health, Evanston, Illinois., Morimoto SS; Population Health Sciences, Division of Health Systems Innovation and Research, University of Utah School of Medicine, Salt Lake City., Lee-Iannotti JK; Department of Neurology, Barrow Neurological Institute, University of Arizona College of Medicine-Phoenix, Phoenix., Killgore WDS; Department of Psychiatry, University of Arizona, Tucson., Dwyer B; Chobanian & Avedisian School of Medicine at Boston University, Boston, Massachusetts., Stringer W; Department of Medicine, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California., Isache C; Department of Medicine, University of Florida-Jacksonville, Jacksonville., Frontera JA; Department of Neurology, Grossman School of Medicine, New York University, New York., Krishnan JA; Department of Medicine, Illinois Research Network and University of Illinois Chicago, Chicago., O'Steen A; Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina., James M; Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina., Harper BL; Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina., Zimmerman KO; Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina.; Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina.
Corporate Authors: RECOVER-NEURO Clinical Trial Group
Source: JAMA neurology [JAMA Neurol] 2026 Jan 01; Vol. 83 (1), pp. 49-59.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589536 Publication Model: Print Cited Medium: Internet ISSN: 2168-6157 (Electronic) Linking ISSN: 21686149 NLM ISO Abbreviation: JAMA Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:2168-6157
DOI:10.1001/jamaneurol.2025.4415