Chromatin remodeling enhances MAP3K8 expression in HAM: a key pathogenesis for therapeutic intervention.
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| Title: | Chromatin remodeling enhances MAP3K8 expression in HAM: a key pathogenesis for therapeutic intervention. |
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| Authors: | Nakashima M; Department of Rare Diseases Research, Institute of Medical Science, St. Marianna University School of Medicine, Kanagawa, Japan., Nagai K; Laboratory of Tumor Cell Biology, Department of Medical Genome Sciences, Graduate School of Frontier Sciences, University of Tokyo, Tokyo, Japan., Takao N; Department of Neurology, St. Marianna University School of Medicine, Kanagawa, Japan., Araya N; Department of Rare Diseases Research, Institute of Medical Science, St. Marianna University School of Medicine, Kanagawa, Japan., Kuze Y; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan., Mizuike J; Laboratory of Tumor Cell Biology, Department of Medical Genome Sciences, Graduate School of Frontier Sciences, University of Tokyo, Tokyo, Japan., Tosaka S; Laboratory of Tumor Cell Biology, Department of Medical Genome Sciences, Graduate School of Frontier Sciences, University of Tokyo, Tokyo, Japan.; Laboratory of Viral Oncology and Genomics, Department of Medical Genome Sciences, Graduate School of Frontier Sciences, University of Tokyo, Tokyo, Japan., Aratani S; Department of Rare Diseases Research, Institute of Medical Science, St. Marianna University School of Medicine, Kanagawa, Japan.; LSI Medience Co, Tokyo, Japan., Yagishita N; Department of Rare Diseases Research, Institute of Medical Science, St. Marianna University School of Medicine, Kanagawa, Japan., Horibe E; Department of Rare Diseases Research, Institute of Medical Science, St. Marianna University School of Medicine, Kanagawa, Japan., Watanabe T; Department of Hematology, St. Marianna University School of Medicine, Kanagawa, Japan., Sato T; Department of Rare Diseases Research, Institute of Medical Science, St. Marianna University School of Medicine, Kanagawa, Japan.; Department of Neurology, St. Marianna University School of Medicine, Kanagawa, Japan., Nannya Y; Division of Hematopoietic Disease Control, The Institute of Medical Science, the University of Tokyo, Tokyo, Japan.; Department of Hematology/Oncology, IMSUT Hospital, The Institute of Medical Science, the University of Tokyo, Tokyo, Japan., Suzuki Y; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan., Uchimaru K; Laboratory of Tumor Cell Biology, Department of Medical Genome Sciences, Graduate School of Frontier Sciences, University of Tokyo, Tokyo, Japan., Yamagishi M; Laboratory of Tumor Cell Biology, Department of Medical Genome Sciences, Graduate School of Frontier Sciences, University of Tokyo, Tokyo, Japan. myamagishi@edu.k.u-tokyo.ac.jp.; Laboratory of Viral Oncology and Genomics, Department of Medical Genome Sciences, Graduate School of Frontier Sciences, University of Tokyo, Tokyo, Japan. myamagishi@edu.k.u-tokyo.ac.jp., Yamano Y; Department of Rare Diseases Research, Institute of Medical Science, St. Marianna University School of Medicine, Kanagawa, Japan. yyamano@marianna-u.ac.jp.; Department of Neurology, St. Marianna University School of Medicine, Kanagawa, Japan. yyamano@marianna-u.ac.jp. |
| Source: | Nature communications [Nat Commun] 2025 Nov 10; Vol. 16 (1), pp. 9874. Date of Electronic Publication: 2025 Nov 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-64836-7 |
