LUBAC modulates CBM complex functions downstream of TRAF6 in T cells.
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| Title: | LUBAC modulates CBM complex functions downstream of TRAF6 in T cells. |
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| Authors: | Graß C; Signaling and Immunity, Research Unit Signaling and Translation, Molecular Targets and Therapeutics Center, Helmholtz Munich - German Research Center for Environmental Health, Neuherberg, Germany., Ober F; Signaling and Immunity, Research Unit Signaling and Translation, Molecular Targets and Therapeutics Center, Helmholtz Munich - German Research Center for Environmental Health, Neuherberg, Germany., Sixt C; Signaling and Immunity, Research Unit Signaling and Translation, Molecular Targets and Therapeutics Center, Helmholtz Munich - German Research Center for Environmental Health, Neuherberg, Germany., Moud BN; Signaling and Immunity, Research Unit Signaling and Translation, Molecular Targets and Therapeutics Center, Helmholtz Munich - German Research Center for Environmental Health, Neuherberg, Germany., Antoshkina I; Signaling and Immunity, Research Unit Signaling and Translation, Molecular Targets and Therapeutics Center, Helmholtz Munich - German Research Center for Environmental Health, Neuherberg, Germany., Eberstadt F; Signaling and Immunity, Research Unit Signaling and Translation, Molecular Targets and Therapeutics Center, Helmholtz Munich - German Research Center for Environmental Health, Neuherberg, Germany., Puhach A; Department of Infection Immunology, Leibniz Institute for Natural Product Research and Infection Biology, Jena, Germany., Avar G; Computational Health Center, Helmholtz Munich, Neuherberg, Germany.; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia., Keßler A; Signaling and Immunity, Research Unit Signaling and Translation, Molecular Targets and Therapeutics Center, Helmholtz Munich - German Research Center for Environmental Health, Neuherberg, Germany., O'Neill TJ; Signaling and Immunity, Research Unit Signaling and Translation, Molecular Targets and Therapeutics Center, Helmholtz Munich - German Research Center for Environmental Health, Neuherberg, Germany., Seeholzer T; Signaling and Immunity, Research Unit Signaling and Translation, Molecular Targets and Therapeutics Center, Helmholtz Munich - German Research Center for Environmental Health, Neuherberg, Germany., Kranich J; Institute for Immunology, Faculty of Medicine, Biomedical Center Munich, Ludwig-Maximilians-Universität, Munich, Germany., Brocker T; Institute for Immunology, Faculty of Medicine, Biomedical Center Munich, Ludwig-Maximilians-Universität, Munich, Germany., Lammens K; Gene Center, Ludwig-Maximilians-Universität, Munich, Germany., Menden MP; Computational Health Center, Helmholtz Munich, Neuherberg, Germany.; Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia., Zielinski CE; Department of Infection Immunology, Leibniz Institute for Natural Product Research and Infection Biology, Jena, Germany.; Infection Immunology, Friedrich Schiller University, Jena, Germany., Krappmann D; Signaling and Immunity, Research Unit Signaling and Translation, Molecular Targets and Therapeutics Center, Helmholtz Munich - German Research Center for Environmental Health, Neuherberg, Germany. daniel.krappmann@helmholtz-munich.de.; Faculty of Biology, Ludwig-Maximilians-Universität, Munich, Germany. daniel.krappmann@helmholtz-munich.de. |
| Source: | Nature communications [Nat Commun] 2025 Nov 10; Vol. 16 (1), pp. 9899. Date of Electronic Publication: 2025 Nov 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-65879-6 |
