CRISPR/Cas9-mediated deletion of MADD induces cell cycle arrest and apoptosis in anaplastic thyroid cancer cells.
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| Title: | CRISPR/Cas9-mediated deletion of MADD induces cell cycle arrest and apoptosis in anaplastic thyroid cancer cells. |
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| Authors: | Bakthavachalam V; Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL, 60612, USA., Sanborn MA; Department of Biochemistry and Molecular Genetics, University of Illinois College of Medicine, Chicago, IL, 60607, USA., Mathayan M; Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL, 60612, USA., Salunkhe SS; Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL, 60612, USA., Wood JM; Research Informatics Core, University of Illinois at Chicago, Chicago, IL, 60612, USA., Maienschein-Cline M; Research Informatics Core, University of Illinois at Chicago, Chicago, IL, 60612, USA., Setty S; Department of Pathology, University of Illinois College of Medicine, Chicago, IL, 60612, USA., Kabeer BSA; Center for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India., Rehman J; Department of Biochemistry and Molecular Genetics, University of Illinois College of Medicine, Chicago, IL, 60607, USA.; University of Illinois Cancer Center, Chicago, IL, 60612, USA., Prabhakar BS; Scientist Jesse Brown VA Medical Center, Chicago, IL, 60612, USA. bprabhak@uic.edu.; University of Illinois Cancer Center, Chicago, IL, 60612, USA. bprabhak@uic.edu.; Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, IL, 60612, USA. bprabhak@uic.edu. |
| Source: | Scientific reports [Sci Rep] 2025 Nov 10; Vol. 15 (1), pp. 39264. Date of Electronic Publication: 2025 Nov 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-025-22907-1 |
