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Histone demethylase KDM4C confers temozolomide resistance to glioblastoma cells by epigenetically regulating E2F6.

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Title: Histone demethylase KDM4C confers temozolomide resistance to glioblastoma cells by epigenetically regulating E2F6.
Authors: Kim GW; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, 85 Songdogwahak-Ro, Yeonsu-Gu, Incheon, 21983, Republic of Korea., Lee DH; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, 85 Songdogwahak-Ro, Yeonsu-Gu, Incheon, 21983, Republic of Korea., Yoo J; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, 85 Songdogwahak-Ro, Yeonsu-Gu, Incheon, 21983, Republic of Korea., Jeon YH; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, 85 Songdogwahak-Ro, Yeonsu-Gu, Incheon, 21983, Republic of Korea., Lee SW; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, 85 Songdogwahak-Ro, Yeonsu-Gu, Incheon, 21983, Republic of Korea., Oh SY; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, 85 Songdogwahak-Ro, Yeonsu-Gu, Incheon, 21983, Republic of Korea., Kwon SH; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, 85 Songdogwahak-Ro, Yeonsu-Gu, Incheon, 21983, Republic of Korea. soheekwon@yonsei.ac.kr.
Source: Archives of pharmacal research [Arch Pharm Res] 2025 Dec; Vol. 48 (11-12), pp. 1345-1361. Date of Electronic Publication: 2025 Nov 11.
Publication Type: Journal Article
Journal Info: Publisher: Pharmaceutical Society of Korea Country of Publication: Korea (South) NLM ID: 8000036 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1976-3786 (Electronic) Linking ISSN: 02536269 NLM ISO Abbreviation: Arch Pharm Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1976-3786
DOI:10.1007/s12272-025-01580-y