pH-responsive Oral liposomal delivery of hydrogen sulfide donor GYY4137 enables colon-targeted therapy for inflammatory bowel disease.
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| Title: | pH-responsive Oral liposomal delivery of hydrogen sulfide donor GYY4137 enables colon-targeted therapy for inflammatory bowel disease. |
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| Authors: | Oh C; Department of Applied Bioengineering, Graduates School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea.; Precision Vaccines Program, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Hwang JE; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea., Yim H; Department of Applied Bioengineering, Graduates School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea., Park H; Research Institute for Convergence Science, Seoul National University, Seoul, 08826, Republic of Korea., Kim SY; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea., Lee JK; Department of Applied Bioengineering, Graduates School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea.; Research Institute for Convergence Science, Seoul National University, Seoul, 08826, Republic of Korea., Im HJ; Department of Applied Bioengineering, Graduates School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea. iiihjjj@gmail.com.; Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea. iiihjjj@gmail.com.; Cancer Research Institute, Seoul National University, Seoul, 03080, Republic of Korea. iiihjjj@gmail.com.; Research Institute for Convergence Science, Seoul National University, Seoul, 08826, Republic of Korea. iiihjjj@gmail.com. |
| Source: | Journal of nanobiotechnology [J Nanobiotechnology] 2025 Nov 11; Vol. 23 (1), pp. 712. Date of Electronic Publication: 2025 Nov 11. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-3155 (Electronic) Linking ISSN: 14773155 NLM ISO Abbreviation: J Nanobiotechnology Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1477-3155 |
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| DOI: | 10.1186/s12951-025-03753-9 |
