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Topical ROCEN (nanoliposomal avocado/soybean unsaponifiables) enhances survival of random-pattern skin flaps through Akt/mTOR pathway modulation.

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Title: Topical ROCEN (nanoliposomal avocado/soybean unsaponifiables) enhances survival of random-pattern skin flaps through Akt/mTOR pathway modulation.
Authors: Mehrabi MM; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.; School of Medicine, Tehran University of Medical Sciences, Tehran, Iran., Ghasemi M; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.; Department of Toxicology & Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran., Hamaneh AM; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.; Department of Toxicology & Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran., Esmaeili Z; Department of Toxicology & Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran., Ashtari S; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.; School of Medicine, Tehran University of Medical Sciences, Tehran, Iran., Nejati F; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.; Department of Toxicology & Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran., Goudarzi R; Division of Research and Development, LLC, Pharmin, San Jose, CA, USA., Tavangar SM; Department of Pathology, Dr. Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran., Dehpour AR; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.; Department of Toxicology & Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran., Partoazar A; Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran. Partoazar@tums.ac.ir.
Source: Molecular biology reports [Mol Biol Rep] 2025 Nov 12; Vol. 53 (1), pp. 72. Date of Electronic Publication: 2025 Nov 12.
Publication Type: Journal Article
Journal Info: Publisher: Reidel Country of Publication: Netherlands NLM ID: 0403234 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-4978 (Electronic) Linking ISSN: 03014851 NLM ISO Abbreviation: Mol Biol Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1573-4978
DOI:10.1007/s11033-025-11240-5