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IgM Anti-Ganglioside Binding and Complement Activation in an iPSC-Derived Motor Neuron Model for Multifocal Motor Neuropathy.

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Title: IgM Anti-Ganglioside Binding and Complement Activation in an iPSC-Derived Motor Neuron Model for Multifocal Motor Neuropathy.
Authors: Krijgsman D; Center for Translational Immunology, UMC Utrecht, the Netherlands., Dijkxhoorn K; Center for Translational Immunology, UMC Utrecht, the Netherlands., de Zeeuw E; Center for Translational Immunology, UMC Utrecht, the Netherlands., Bloemenkamp LM; Center for Translational Immunology, UMC Utrecht, the Netherlands.; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, the Netherlands.; Department of Translational Neuroscience, UMC Utrecht Brain Center, Utrecht University, the Netherlands., Bos JW; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, the Netherlands., van Eijk RPA; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, the Netherlands., Van de Walle I; argenx, Ghent, Belgium., Huizinga R; Department of Immunology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands; and., Jacobs BC; Department of Immunology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands; and.; Department of Neurology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands., Leusen JHW; Center for Translational Immunology, UMC Utrecht, the Netherlands., Pasterkamp RJ; Department of Translational Neuroscience, UMC Utrecht Brain Center, Utrecht University, the Netherlands., Hack CE; Center for Translational Immunology, UMC Utrecht, the Netherlands., Budding K; Center for Translational Immunology, UMC Utrecht, the Netherlands.; argenx, Ghent, Belgium., van der Pol WL; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, the Netherlands.
Source: Neurology(R) neuroimmunology & neuroinflammation [Neurol Neuroimmunol Neuroinflamm] 2026 Jan; Vol. 13 (1), pp. e200482. Date of Electronic Publication: 2025 Nov 12.
Publication Type: Journal Article
Journal Info: Publisher: Wolters Kluwer Health/Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101636388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2332-7812 (Electronic) Linking ISSN: 23327812 NLM ISO Abbreviation: Neurol Neuroimmunol Neuroinflamm Subsets: MEDLINE
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  Data: IgM Anti-Ganglioside Binding and Complement Activation in an iPSC-Derived Motor Neuron Model for Multifocal Motor Neuropathy.
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  Data: <searchLink fieldCode="AU" term="%22Krijgsman+D%22">Krijgsman D</searchLink>; Center for Translational Immunology, UMC Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Dijkxhoorn+K%22">Dijkxhoorn K</searchLink>; Center for Translational Immunology, UMC Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Zeeuw+E%22">de Zeeuw E</searchLink>; Center for Translational Immunology, UMC Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Bloemenkamp+LM%22">Bloemenkamp LM</searchLink>; Center for Translational Immunology, UMC Utrecht, the Netherlands.; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, the Netherlands.; Department of Translational Neuroscience, UMC Utrecht Brain Center, Utrecht University, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Bos+JW%22">Bos JW</searchLink>; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Eijk+RPA%22">van Eijk RPA</searchLink>; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Van+de+Walle+I%22">Van de Walle I</searchLink>; argenx, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Huizinga+R%22">Huizinga R</searchLink>; Department of Immunology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands; and.<br /><searchLink fieldCode="AU" term="%22Jacobs+BC%22">Jacobs BC</searchLink>; Department of Immunology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands; and.; Department of Neurology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Leusen+JHW%22">Leusen JHW</searchLink>; Center for Translational Immunology, UMC Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Pasterkamp+RJ%22">Pasterkamp RJ</searchLink>; Department of Translational Neuroscience, UMC Utrecht Brain Center, Utrecht University, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Hack+CE%22">Hack CE</searchLink>; Center for Translational Immunology, UMC Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Budding+K%22">Budding K</searchLink>; Center for Translational Immunology, UMC Utrecht, the Netherlands.; argenx, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22van+der+Pol+WL%22">van der Pol WL</searchLink>; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, the Netherlands.
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  Data: <searchLink fieldCode="JN" term="%22101636388%22">Neurology(R) neuroimmunology & neuroinflammation</searchLink> [Neurol Neuroimmunol Neuroinflamm] 2026 Jan; Vol. 13 (1), pp. e200482. <i>Date of Electronic Publication: </i>2025 Nov 12.
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              Text: 2026 Jan
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