Real-world safety and age-dependent effectiveness of vosoritide in achondroplasia: A single-center retrospective analysis of transition from growth hormone to vosoritide.
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| Title: | Real-world safety and age-dependent effectiveness of vosoritide in achondroplasia: A single-center retrospective analysis of transition from growth hormone to vosoritide. |
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| Authors: | Shimada T; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address: t.shimada@ped.med.osaka-u.ac.jp., Nakayama H; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan; Department of Oral and Maxillofacial Surgery, School & Graduate School of Dentistry, The University of Osaka, 1-8 Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address: nkhirofumi@ped.med.osaka-u.ac.jp., Ueda I; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address: i.ueda@ped.med.osaka-u.ac.jp., Ishimi T; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address: takeshi.ishimi517@ped.med.osaka-u.ac.jp., Yamada C; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address: c.yamada@ped.med.osaka-u.ac.jp., Nakano Y; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address: yuccayuka1977@gmail.com., Yamamoto K; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan; Division of Health Sciences, The University of Osaka Graduate School of Medicine, 1-7 Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address: ken.y.2015@ped.med.osaka-u.ac.jp., Fujiwara M; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address: makotof@ped.med.osaka-u.ac.jp., Kitaoka T; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan; Department of Pediatrics, ISEIKAI International General Hospital, 4-14 Minamiogi-machi, Kita-ku, Osaka, Osaka, 530-0052, Japan. Electronic address: tkitaoka@ped.med.osaka-u.ac.jp., Ozono K; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan; Center for Promoting Treatment of Intractable Diseases, ISEIKAI International General Hospital, 4-14 Minamiogi-machi, Kita-ku, Osaka, Osaka, 530-0052, Japan. Electronic address: keioz@ped.med.osaka-u.ac.jp., Kubota T; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan; Department of Pediatric Nephrology and Metabolism, Osaka Women's and Children's Hospital, Osaka Prefectural Hospital Organization, 840 Murodocho, Izumi, Osaka, 594-1101, Japan. Electronic address: kubotat@wch.opho.jp., Ohata Y; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address: yasuhisa1@ped.med.osaka-u.ac.jp., Kitabatake Y; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address: ykitaba@ped.med.osaka-u.ac.jp. |
| Source: | Bone [Bone] 2026 Feb; Vol. 203, pp. 117722. Date of Electronic Publication: 2025 Nov 11. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science Country of Publication: United States NLM ID: 8504048 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2763 (Electronic) Linking ISSN: 18732763 NLM ISO Abbreviation: Bone Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41232919 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Real-world safety and age-dependent effectiveness of vosoritide in achondroplasia: A single-center retrospective analysis of transition from growth hormone to vosoritide. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Shimada+T%22">Shimada T</searchLink>; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address: t.shimada@ped.med.osaka-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Nakayama+H%22">Nakayama H</searchLink>; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan; Department of Oral and Maxillofacial Surgery, School & Graduate School of Dentistry, The University of Osaka, 1-8 Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address: nkhirofumi@ped.med.osaka-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Ueda+I%22">Ueda I</searchLink>; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address: i.ueda@ped.med.osaka-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Ishimi+T%22">Ishimi T</searchLink>; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address: takeshi.ishimi517@ped.med.osaka-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Yamada+C%22">Yamada C</searchLink>; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address: c.yamada@ped.med.osaka-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Nakano+Y%22">Nakano Y</searchLink>; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address: yuccayuka1977@gmail.com.<br /><searchLink fieldCode="AU" term="%22Yamamoto+K%22">Yamamoto K</searchLink>; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan; Division of Health Sciences, The University of Osaka Graduate School of Medicine, 1-7 Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address: ken.y.2015@ped.med.osaka-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Fujiwara+M%22">Fujiwara M</searchLink>; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address: makotof@ped.med.osaka-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Kitaoka+T%22">Kitaoka T</searchLink>; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan; Department of Pediatrics, ISEIKAI International General Hospital, 4-14 Minamiogi-machi, Kita-ku, Osaka, Osaka, 530-0052, Japan. Electronic address: tkitaoka@ped.med.osaka-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Ozono+K%22">Ozono K</searchLink>; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan; Center for Promoting Treatment of Intractable Diseases, ISEIKAI International General Hospital, 4-14 Minamiogi-machi, Kita-ku, Osaka, Osaka, 530-0052, Japan. Electronic address: keioz@ped.med.osaka-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Kubota+T%22">Kubota T</searchLink>; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan; Department of Pediatric Nephrology and Metabolism, Osaka Women's and Children's Hospital, Osaka Prefectural Hospital Organization, 840 Murodocho, Izumi, Osaka, 594-1101, Japan. Electronic address: kubotat@wch.opho.jp.<br /><searchLink fieldCode="AU" term="%22Ohata+Y%22">Ohata Y</searchLink>; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address: yasuhisa1@ped.med.osaka-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Kitabatake+Y%22">Kitabatake Y</searchLink>; Department of Pediatrics, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address: ykitaba@ped.med.osaka-u.ac.jp. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228504048%22">Bone</searchLink> [Bone] 2026 Feb; Vol. 203, pp. 117722. <i>Date of Electronic Publication: </i>2025 Nov 11. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8504048 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-2763 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218732763%22">18732763 </searchLink><i>NLM ISO Abbreviation: </i>Bone <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41232919 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.bone.2025.117722 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 117722 Titles: – TitleFull: Real-world safety and age-dependent effectiveness of vosoritide in achondroplasia: A single-center retrospective analysis of transition from growth hormone to vosoritide. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Shimada T – PersonEntity: Name: NameFull: Nakayama H – PersonEntity: Name: NameFull: Ueda I – PersonEntity: Name: NameFull: Ishimi T – PersonEntity: Name: NameFull: Yamada C – PersonEntity: Name: NameFull: Nakano Y – PersonEntity: Name: NameFull: Yamamoto K – PersonEntity: Name: NameFull: Fujiwara M – PersonEntity: Name: NameFull: Kitaoka T – PersonEntity: Name: NameFull: Ozono K – PersonEntity: Name: NameFull: Kubota T – PersonEntity: Name: NameFull: Ohata Y – PersonEntity: Name: NameFull: Kitabatake Y IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: 2026 Feb Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1873-2763 Numbering: – Type: volume Value: 203 Titles: – TitleFull: Bone Type: main |
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