Multi-omics analysis of a pig-to-human decedent kidney xenotransplant.

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Bibliographic Details
Title: Multi-omics analysis of a pig-to-human decedent kidney xenotransplant.
Authors: Schmauch E; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA., Piening BD; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, OR, USA.; Providence Institute for Clinical Innovation, Providence Health, Portland, OR, USA., Dowdell AK; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, OR, USA.; Providence Institute for Clinical Innovation, Providence Health, Portland, OR, USA., Mohebnasab M; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Williams SH; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Stukalov A; Seer, Redwood City, CA, USA., Robinson FL; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, OR, USA., Bombardi R; Illumina, San Diego, CA, USA., Jaffe I; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Khalil K; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Kim J; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Aljabban I; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Eitan T; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., O'Brien DP; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Rophina M; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Wang C; Department of Population Health, NYU Grossman School of Medicine, New York, NY, USA., Bartlett AQ; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, OR, USA., Zanoni F; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA.; Unit of Nephrology, Dialysis, and Kidney Transplantation, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Albay J; Department of Medicine, NYU Grossman School of Medicine, New York, NY, USA., Andrijevic D; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Maden B; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Mauduit V; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Vikman S; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Argibay D; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Zayas Z; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Wu L; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Moi K; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Lau B; Department of Medicine, Division of Oncology, Stanford University, Stanford, CA, USA., Zhang W; Institute for Systems Genetics, NYU Langone Health, New York, NY, USA., Gragert L; Department of Pathology and Laboratory Medicine, Tulane University, New Orleans, LA, USA., Weldon E; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Gao H; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Hamilton L; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, OR, USA., Kagermazova L; Institute for Systems Genetics, NYU Langone Health, New York, NY, USA., Camellato BR; Institute for Systems Genetics, NYU Langone Health, New York, NY, USA., Gandla D; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Bhatt R; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Gao S; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Al-Ali RA; Department of Internal Medicine, King Fahd Hospital of the University, Alkhobar, Saudi Arabia., Habara AH; Department of Clinical Biochemistry, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia., Chang A; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Ferdosi S; Seer, Redwood City, CA, USA., Chen HM; Department of Medicine, NYU Grossman School of Medicine, New York, NY, USA., Motter JD; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Thomas SC; Department of Molecular Pathobiology, New York University College of Dentistry, New York, NY, USA., Saxena D; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA.; Department of Molecular Pathobiology, New York University College of Dentistry, New York, NY, USA., Fairchild RL; Department of Immunology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA., Loupy A; Paris Transplant Group, INSERM, Paris, France., Heguy A; Genome Technology center, NYU Langone Health, New York, NY, USA., Crawford A; Illumina, San Diego, CA, USA., Batzoglou S; Seer, Redwood City, CA, USA., Snyder MP; Department of Medicine, Division of Oncology, Stanford University, Stanford, CA, USA., Siddiqui A; Seer, Redwood City, CA, USA., Holmes MV; Medical Research Council, Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Chong AS; Department of Surgery, The University of Chicago, Chicago, IL, USA., Kaikkonen MU; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Linna-Kuosmanen S; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ayares D; Revivicor, Blacksburg, VA, USA., Lorber M; United Therapeutics, Silver Spring, MD, USA., Nellore A; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA., Skolnik EY; Department of Medicine, NYU Grossman School of Medicine, New York, NY, USA., Mattoo A; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA., Tatapudi VS; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Taft R; Illumina, San Diego, CA, USA., Mangiola M; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Guo Q; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Herati RS; Department of Medicine, NYU Grossman School of Medicine, New York, NY, USA., Stern J; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Griesemer A; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Kellis M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA., Boeke JD; Institute for Systems Genetics, NYU Langone Health, New York, NY, USA., Montgomery RA; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Keating BJ; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA. brendan.keating@nyulangone.org.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA. brendan.keating@nyulangone.org.; Institute for Systems Genetics, NYU Langone Health, New York, NY, USA. brendan.keating@nyulangone.org.
Source: Nature [Nature] 2026 Feb; Vol. 650 (8100), pp. 205-217. Date of Electronic Publication: 2025 Nov 13.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-4687
DOI:10.1038/s41586-025-09846-7