Immunologic Profiling Suggests an Association Between Treg Cell Dysfunction and Pain in Knee Osteoarthritis.

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Title: Immunologic Profiling Suggests an Association Between Treg Cell Dysfunction and Pain in Knee Osteoarthritis.
Authors: Binvignat M; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France.; Centre de Recherche Saint-Antoine, INSERM UMRS-938, Sorbonne Université, Paris, France.; Department of Rheumatology, Saint-Antoine Hospital, AP-HP, Paris, France., Dubois J; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France., Marco Salvador M; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France., Stys P; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France., Pitoiset F; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France., Roux A; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France., Sastre M; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France., Hassler S; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France., Lorenzon R; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France.; Biotherapy and Inflammation-Immunopathology-Biotherapy Department, AP-HP, Paris, France., Ribet C; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France.; Biotherapy and Inflammation-Immunopathology-Biotherapy Department, AP-HP, Paris, France., Mhanna V; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France., Vantomme H; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France., Adda L; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France., Barennes P; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France., Coatnoan N; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France., Le Gouge K; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France., Aheng C; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France., Courties A; Centre de Recherche Saint-Antoine, INSERM UMRS-938, Sorbonne Université, Paris, France.; Department of Rheumatology, Saint-Antoine Hospital, AP-HP, Paris, France., Minssen L; Department of Radiology, Saint-Antoine Hospital, AP-HP, Paris, France., Butte AJ; Bakar Computational Health Science Institute, University of California, San Francisco., Six A; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France., Rosenzwajg M; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France., Tchitchek N; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France., Berenbaum F; Centre de Recherche Saint-Antoine, INSERM UMRS-938, Sorbonne Université, Paris, France.; Department of Rheumatology, Saint-Antoine Hospital, AP-HP, Paris, France., Klatzmann D; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France.; Biotherapy and Inflammation-Immunopathology-Biotherapy Department, AP-HP, Paris, France., Mariotti-Ferrandiz E; Immunoregulation, Immunopathology, Immunotherapy I3 Laboratory, INSERM UMRS-959, Sorbonne Université, Paris, France.; Institut Universitaire de France, Paris, France., Sellam J; Centre de Recherche Saint-Antoine, INSERM UMRS-938, Sorbonne Université, Paris, France.; Department of Rheumatology, Saint-Antoine Hospital, AP-HP, Paris, France.
Source: Arthritis & rheumatology (Hoboken, N.J.) [Arthritis Rheumatol] 2026 Apr; Vol. 78 (4), pp. 848-860. Date of Electronic Publication: 2026 Feb 05.
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101623795 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2326-5205 (Electronic) Linking ISSN: 23265191 NLM ISO Abbreviation: Arthritis Rheumatol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2326-5205
DOI:10.1002/art.43437