Safety and efficacy of weekly pemvidutide versus placebo for metabolic dysfunction-associated steatohepatitis (IMPACT): 24-week results from a multicentre, randomised, double-blind, phase 2b study.

Saved in:
Bibliographic Details
Title: Safety and efficacy of weekly pemvidutide versus placebo for metabolic dysfunction-associated steatohepatitis (IMPACT): 24-week results from a multicentre, randomised, double-blind, phase 2b study.
Authors: Noureddin M; Houston Methodist Hospital, Houston, TX, USA; Houston Research Institute, Houston, TX, USA. Electronic address: mnoureddin@houstonmethodist.org., Harrison SA; Pinnacle Clinical Research, San Antonio, TX, USA., Loomba R; MASLD Research Center, Division of Gastroenterology and Hepatology, University of California at San Diego, La Jolla, California, USA., Alkhouri N; Summit Clinical Research, San Antonio, TX, USA; Clinical Research Institute of Ohio, Westlake, OH, USA., Chalasani N; Indiana University School of Medicine, Indianapolis, IN, USA., Sheikh MY; Fresno Clinical Research Center, Fresno, CA, USA., Tomah S; Altimmune, Gaithersburg, MD, USA., Gutierrez JA; Altimmune, Gaithersburg, MD, USA; Scripps Clinic, La Jolla, CA, USA., Urbina S; Altimmune, Gaithersburg, MD, USA., Suschak JJ; Altimmune, Gaithersburg, MD, USA., Brown R; Altimmune, Gaithersburg, MD, USA., Odili O; Altimmune, Gaithersburg, MD, USA., Yang J; Altimmune, Gaithersburg, MD, USA., Keeton S; Altimmune, Gaithersburg, MD, USA., Neff G; Covenant Metabolic Specialists, Fort Myers, FL, USA., Mena E; California Liver Research Institute, Pasadena, CA, USA., Roberts MS; Altimmune, Gaithersburg, MD, USA., Browne SK; Altimmune, Gaithersburg, MD, USA., Harris MS; Altimmune, Gaithersburg, MD, USA.
Source: Lancet (London, England) [Lancet] 2025 Dec 06; Vol. 406 (10520), pp. 2644-2655. Date of Electronic Publication: 2025 Nov 11.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II; Multicenter Study
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 2985213R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-547X (Electronic) Linking ISSN: 01406736 NLM ISO Abbreviation: Lancet Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1474-547X
DOI:10.1016/S0140-6736(25)02114-2