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Selective membrane disrupting dispiro-oxindole Dehydrocostuslactone hybrids with potent anti-MRSA, antibiofilm, and synergistic activity.

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Bibliographic Details
Title: Selective membrane disrupting dispiro-oxindole Dehydrocostuslactone hybrids with potent anti-MRSA, antibiofilm, and synergistic activity.
Authors: Bhushan A; Natural Products and Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India., Rathore A; Infectious Diseases Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India., Baghel VS; Natural Products and Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India., Firdous S; Infectious Diseases Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India., Dhiman U; Natural Products and Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India., Sarkar B; Infectious Diseases Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India., Bharitkar YP; Natural Products and Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India., Gupta P; Natural Products and Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India. Electronic address: guptap.iiim@csir.res.in., Mahapa A; Infectious Diseases Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India. Electronic address: avisekmahapa.iiim@csir.res.in., Phatake RS; Natural Products and Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India. Electronic address: ravindraphatake.iiim@csir.res.in.
Source: Bioorganic chemistry [Bioorg Chem] 2025 Dec; Vol. 167, pp. 109230. Date of Electronic Publication: 2025 Nov 10.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1090-2120
DOI:10.1016/j.bioorg.2025.109230