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Nanoformulation of a Pin1 inhibitor potentiates the efficacy of liposomal doxorubicin in second-line therapy for ovarian cancer.

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Title: Nanoformulation of a Pin1 inhibitor potentiates the efficacy of liposomal doxorubicin in second-line therapy for ovarian cancer.
Authors: Saorin G; Department of Molecular Sciences and Nanosystems, Ca' Foscari University of Venice, 30172, Venice, Italy., Mauceri M; Department of Molecular Sciences and Nanosystems, Ca' Foscari University of Venice, 30172, Venice, Italy., Caligiuri I; Pathology Unit, Centro di Riferimento Oncologico di Aviano (C.R.O.) IRCCS, 33081, Aviano, Italy. Electronic address: isabella.caligiuri@cro.it., Kamensek U; Department of Experimental Oncology, Institute of Oncology Ljubljana, Zaloska cesta 5, SI-1000, Ljubljana, Slovenia., Kranjc Brezar S; Department of Experimental Oncology, Institute of Oncology Ljubljana, Zaloska cesta 5, SI-1000, Ljubljana, Slovenia., Corona G; Immunopathology and Cancer Biomarkers, Centro di Riferimento Oncologico di Aviano (C.R.O.) IRCCS, 33081, Aviano, Italy., Repetto O; Immunopathology and Cancer Biomarkers, Centro di Riferimento Oncologico di Aviano (C.R.O.) IRCCS, 33081, Aviano, Italy., Perin T; Pathology Unit, Centro di Riferimento Oncologico di Aviano (C.R.O.) IRCCS, 33081, Aviano, Italy., Grassi G; Clinical Department of Medical, Surgical and Health Sciences, Cattinara University Hospital, Trieste Univer-sity, Trieste, Italy., Granchi C; Department of Pharmacy, University of Pisa, 56124, Pisa, Italy., Tuccinardi T; Department of Pharmacy, University of Pisa, 56124, Pisa, Italy., Cemazar M; Department of Experimental Oncology, Institute of Oncology Ljubljana, Zaloska cesta 5, SI-1000, Ljubljana, Slovenia., Canzonieri V; Pathology Unit, Centro di Riferimento Oncologico di Aviano (C.R.O.) IRCCS, 33081, Aviano, Italy; Department of Medical, Surgical and Health Sciences, University of Trieste, 34149, Trieste, Italy., Adeel M; Department of Molecular Sciences and Nanosystems, Ca' Foscari University of Venice, 30172, Venice, Italy., Rizzolio F; Department of Molecular Sciences and Nanosystems, Ca' Foscari University of Venice, 30172, Venice, Italy; Pathology Unit, Centro di Riferimento Oncologico di Aviano (C.R.O.) IRCCS, 33081, Aviano, Italy. Electronic address: flavio.rizzolio@unive.it.
Source: Cancer letters [Cancer Lett] 2026 Jan 16; Vol. 637, pp. 218128. Date of Electronic Publication: 2025 Nov 13.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1872-7980
DOI:10.1016/j.canlet.2025.218128