Impact of 6-purine modifications on the ribose substrate selectivity of pyrimidine nucleoside phosphorylase (PyNP) in base exchange reactions.

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Title: Impact of 6-purine modifications on the ribose substrate selectivity of pyrimidine nucleoside phosphorylase (PyNP) in base exchange reactions.
Authors: Hatano A; Environment and Materials Engineering, College of Engineering, Shibaura Institute of Technology, 307 Fukasaku, Minuma-ku, Saitama, 337-8570, Japan. Electronic address: a-hatano@sic.shibaura-it.ac.jp., Matsuzaka R; Environment and Materials Engineering, College of Engineering, Shibaura Institute of Technology, 307 Fukasaku, Minuma-ku, Saitama, 337-8570, Japan., Hamano R; Environment and Materials Engineering, College of Engineering, Shibaura Institute of Technology, 307 Fukasaku, Minuma-ku, Saitama, 337-8570, Japan., Shimane G; Environment and Materials Engineering, College of Engineering, Shibaura Institute of Technology, 307 Fukasaku, Minuma-ku, Saitama, 337-8570, Japan., Fukatsu T; Environment and Materials Engineering, College of Engineering, Shibaura Institute of Technology, 307 Fukasaku, Minuma-ku, Saitama, 337-8570, Japan., Okumoto H; Environment and Materials Engineering, College of Engineering, Shibaura Institute of Technology, 307 Fukasaku, Minuma-ku, Saitama, 337-8570, Japan., Kidowaki M; Chemistry and Biotechnology, College of Engineering, Shibaura Institute of Technology, 3-7-5, Toyosu, Koto-ku, Tokyo, 135-8548, Japan., Konishi T; Environment and Materials Engineering, College of Engineering, Shibaura Institute of Technology, 307 Fukasaku, Minuma-ku, Saitama, 337-8570, Japan.
Source: Carbohydrate research [Carbohydr Res] 2026 Jan; Vol. 559, pp. 109739. Date of Electronic Publication: 2025 Nov 13.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0043535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-426X (Electronic) Linking ISSN: 00086215 NLM ISO Abbreviation: Carbohydr Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-426X
DOI:10.1016/j.carres.2025.109739