Exosomal Pparα derived from cancer cells induces CD8 + T cell exhaustion in hepatocellular carcinoma through the miR-27b-3p /TOX axis.
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| Title: | Exosomal Pparα derived from cancer cells induces CD8 + T cell exhaustion in hepatocellular carcinoma through the miR-27b-3p /TOX axis. |
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| Authors: | Zhong W; Department of General Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, Shaanxi 710038, China., Luo N; Department of General Surgery, 943 Hospital of PLA, Wuwei, Gansu 733000, China., Chen Y; Department of General Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, Shaanxi 710038, China., Li J; Department of General Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, Shaanxi 710038, China., Yang Z; Department of General Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, Shaanxi 710038, China., Dong R; Department of General Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, Shaanxi 710038, China. |
| Source: | Chinese medical journal [Chin Med J (Engl)] 2025 Dec 05; Vol. 138 (23), pp. 3139-3152. Date of Electronic Publication: 2025 Nov 17. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Chinese Medical Association ; produced by Wolters Kluwer Country of Publication: China NLM ID: 7513795 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2542-5641 (Electronic) Linking ISSN: 03666999 NLM ISO Abbreviation: Chin Med J (Engl) Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 2542-5641 |
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| DOI: | 10.1097/CM9.0000000000003894 |
