Exosomal Pparα derived from cancer cells induces CD8 + T cell exhaustion in hepatocellular carcinoma through the miR-27b-3p /TOX axis.

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Bibliographic Details
Title: Exosomal Pparα derived from cancer cells induces CD8 + T cell exhaustion in hepatocellular carcinoma through the miR-27b-3p /TOX axis.
Authors: Zhong W; Department of General Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, Shaanxi 710038, China., Luo N; Department of General Surgery, 943 Hospital of PLA, Wuwei, Gansu 733000, China., Chen Y; Department of General Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, Shaanxi 710038, China., Li J; Department of General Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, Shaanxi 710038, China., Yang Z; Department of General Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, Shaanxi 710038, China., Dong R; Department of General Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, Shaanxi 710038, China.
Source: Chinese medical journal [Chin Med J (Engl)] 2025 Dec 05; Vol. 138 (23), pp. 3139-3152. Date of Electronic Publication: 2025 Nov 17.
Publication Type: Journal Article
Journal Info: Publisher: Chinese Medical Association ; produced by Wolters Kluwer Country of Publication: China NLM ID: 7513795 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2542-5641 (Electronic) Linking ISSN: 03666999 NLM ISO Abbreviation: Chin Med J (Engl) Subsets: MEDLINE
Database: MEDLINE Ultimate
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