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Absence of complement terminal pathway activity in C6-deficient mice prolongs survival in a mouse model of severe malarial infection.

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Title: Absence of complement terminal pathway activity in C6-deficient mice prolongs survival in a mouse model of severe malarial infection.
Authors: Kamiya T; Department of Nephrology, Nagoya University Graduate School of Medicine, Nagaya, Japan., Miyasaka Y; Division of Experimental Animals, Nagoya University Graduate School of Medicine, Nagaya, Japan., Kim H; Department of Nephrology, Nagoya University Graduate School of Medicine, Nagaya, Japan; Department of Renal Replacement Therapy, Nagoya University Graduate School of Medicine, Nagaya, Japan., Fukui S; Department of Nephrology, Nagoya University Graduate School of Medicine, Nagaya, Japan; Department of Renal Replacement Therapy, Nagoya University Graduate School of Medicine, Nagaya, Japan., Inoue M; Department of Nephrology, Nagoya University Graduate School of Medicine, Nagaya, Japan., Ishigami M; Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagaya, Japan., Suzuki Y; Department of Nephrology, Nagoya University Graduate School of Medicine, Nagaya, Japan; Department of Renal Replacement Therapy, Nagoya University Graduate School of Medicine, Nagaya, Japan., Maruyama S; Department of Nephrology, Nagoya University Graduate School of Medicine, Nagaya, Japan., Ohno T; Division of Experimental Animals, Nagoya University Graduate School of Medicine, Nagaya, Japan., Hughes TR; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK., Morgan BP; Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK., Mizuno M; Department of Nephrology, Nagoya University Graduate School of Medicine, Nagaya, Japan; Department of Renal Replacement Therapy, Nagoya University Graduate School of Medicine, Nagaya, Japan. Electronic address: mmizu@med.nagoya-u.ac.jp.
Source: Immunobiology [Immunobiology] 2025 Nov; Vol. 230 (6), pp. 153140. Date of Electronic Publication: 2025 Nov 11.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8002742 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3279 (Electronic) Linking ISSN: 01712985 NLM ISO Abbreviation: Immunobiology Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1878-3279
DOI:10.1016/j.imbio.2025.153140