Restarting anticoagulation early versus late in patients with chronic subdural hematoma and atrial fibrillation (RELACS): a phase III international multicenter, randomized controlled, two-arm, assessor-blinded trial.
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| Title: | Restarting anticoagulation early versus late in patients with chronic subdural hematoma and atrial fibrillation (RELACS): a phase III international multicenter, randomized controlled, two-arm, assessor-blinded trial. |
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| Authors: | Raj R; Department of Neurosurgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. rahul.raj@hus.fi., Tommiska P; Department of Neurosurgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Kivisaari R; Department of Neurosurgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Korja M; Department of Neurosurgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Luostarinen T; Anesthesiology and Intensive Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Virta JJ; Anesthesiology and Intensive Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Taimela S; Finnish Centre for Evidence-Based Orthopedics (FICEBO), University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Department of Orthopaedics and Traumatology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Järvinen TLN; Finnish Centre for Evidence-Based Orthopedics (FICEBO), University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Department of Orthopaedics and Traumatology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Niemelä M; Department of Neurosurgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Koivisto T; Department of Neurosurgery, Kuopio University Hospitaland, University of Eastern Finland , Kuopio, Finland., Leinonen V; Department of Neurosurgery, Kuopio University Hospitaland, University of Eastern Finland , Kuopio, Finland., Saemundsson B; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.; Department of Neurosurgery, Karolinska University Hospital, Stockholm, Sweden., Fletcher-Sandersjöö A; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.; Department of Neurosurgery, Karolinska University Hospital, Stockholm, Sweden., Korhonen T; University of Oulu and Medical Research Center, Unit of Clinical Neuroscience, Neurosurgery, Oulu, Finland., Tetri S; University of Oulu and Medical Research Center, Unit of Clinical Neuroscience, Neurosurgery, Oulu, Finland., Rauhala M; Department of Neurosurgery, Tampere University Hospital and Tampere University, Tampere, Finland., Laukka D; Department of Neurosurgery and Turku Brain Injury Center, Turku University Hospital and University of Turku, Turku, Finland., Czuba T; Department of Molecular and Clinical Medicine/The Wallenberg Laboratory, Institute of Medicine, Gothenburg University and the Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden.; Department of Cardiology, Clinical Sciences, Lund University, Lund, Sweden., Bartek J; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.; Department of Neurosurgery, Karolinska University Hospital, Stockholm, Sweden., Danner N; Department of Neurosurgery, Kuopio University Hospitaland, University of Eastern Finland , Kuopio, Finland., Knuutinen O; University of Oulu and Medical Research Center, Unit of Clinical Neuroscience, Neurosurgery, Oulu, Finland., Luoto T; Department of Neurosurgery, Tampere University Hospital and Tampere University, Tampere, Finland., Posti JP; Department of Neurosurgery and Turku Brain Injury Center, Turku University Hospital and University of Turku, Turku, Finland.; Division of Clinical Neurosciences, Neurosurgery, University of Turku, Turku, Finland., Satopää J; Department of Neurosurgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. |
| Source: | Trials [Trials] 2025 Nov 17; Vol. 26 (1), pp. 515. Date of Electronic Publication: 2025 Nov 17. |
| Publication Type: | Journal Article; Clinical Trial Protocol |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1745-6215 |
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| DOI: | 10.1186/s13063-025-09133-w |
