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Self-amplifying RNAs generated with the modified nucleotides 5-methylcytidine and 5-methyluridine mediate strong expression and immunogenicity in vivo.

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Bibliographic Details
Title: Self-amplifying RNAs generated with the modified nucleotides 5-methylcytidine and 5-methyluridine mediate strong expression and immunogenicity in vivo.
Authors: Azizi H; Human Health Therapeutics, National Research Council Canada, Ottawa, Ontario K1A 0R6, Canada., Renner TM; Human Health Therapeutics, National Research Council Canada, Ottawa, Ontario K1A 0R6, Canada., Agbayani G; Human Health Therapeutics, National Research Council Canada, Ottawa, Ontario K1A 0R6, Canada., Simard B; Human Health Therapeutics, National Research Council Canada, Ottawa, Ontario K1A 0R6, Canada., Dudani R; Human Health Therapeutics, National Research Council Canada, Ottawa, Ontario K1A 0R6, Canada., Harrison BA; Human Health Therapeutics, National Research Council Canada, Ottawa, Ontario K1A 0R6, Canada., Iqbal U; Human Health Therapeutics, National Research Council Canada, Ottawa, Ontario K1A 0R6, Canada., Jia Y; Human Health Therapeutics, National Research Council Canada, Ottawa, Ontario K1A 0R6, Canada., McCluskie MJ; Human Health Therapeutics, National Research Council Canada, Ottawa, Ontario K1A 0R6, Canada., Akache B; Human Health Therapeutics, National Research Council Canada, Ottawa, Ontario K1A 0R6, Canada.
Source: NAR molecular medicine [NAR Mol Med] 2024 Apr 09; Vol. 1 (2), pp. ugae004. Date of Electronic Publication: 2024 Apr 09 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9918752080106676 Publication Model: eCollection Cited Medium: Internet ISSN: 2976-856X (Electronic) Linking ISSN: 2976856X NLM ISO Abbreviation: NAR Mol Med Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2976-856X
DOI:10.1093/narmme/ugae004