PRKAA2 mediates the pathogenesis of metabolic dysfunction-associated steatotic liver disease via PI3K/AKT signaling pathway.

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Title: PRKAA2 mediates the pathogenesis of metabolic dysfunction-associated steatotic liver disease via PI3K/AKT signaling pathway.
Authors: Li J; Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China., Wu G; Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China., Li Z; Department of Thoracic Surgery, Liuzhou People's Hospital Affiliated to Guangxi Medical University, Liuzhou, Guangxi, China., Liang X; Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China., Chen Y; Department of Hepatopancreatobiliary Vascular Surgery, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China., Yang B; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China., Xian J; Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China., Deng T; Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China., Chen C; Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China., Li L; Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China., Liu Y; Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China., Xiong T; Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China., Wu S; Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China., Yang X; Department of Geriatric Endocrinology and Metabolism, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China. yangxicc2008@sina.cn., Qin Y; Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China. yingfenq@126.com.
Source: Human genomics [Hum Genomics] 2025 Nov 19; Vol. 19 (1), pp. 136. Date of Electronic Publication: 2025 Nov 19.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101202210 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-7364 (Electronic) Linking ISSN: 14739542 NLM ISO Abbreviation: Hum Genomics Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1479-7364
DOI:10.1186/s40246-025-00854-2