Clinical Trial: Hepatitis B Virus Genotype and a Combination of End-of-Treatment Biomarkers Predict Severe Flares After Nucleos(t)ide Analogue Cessation.

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Title: Clinical Trial: Hepatitis B Virus Genotype and a Combination of End-of-Treatment Biomarkers Predict Severe Flares After Nucleos(t)ide Analogue Cessation.
Authors: Furquim d'Almeida A; Viral Hepatitis Research Group, Laboratory of Experimental Medicine and Pediatrics, University of Antwerp, Antwerp, Belgium.; Department of Gastroenterology and Hepatology, Antwerp University Hospital, Antwerp, Belgium., Vanderlinden A; Viral Hepatitis Research Group, Laboratory of Experimental Medicine and Pediatrics, University of Antwerp, Antwerp, Belgium.; Department of Gastroenterology and Hepatology, Antwerp University Hospital, Antwerp, Belgium., Bourgeois S; Department of Gastroenterology, Ziekenhuis aan de Stroom, Antwerp, Belgium., Mulkay JP; Department of Hepato-Gastroenterology, CHU Saint-Pierre, Brussels, Belgium., Sersté T; Department of Hepato-Gastroenterology, CHU Saint-Pierre, Brussels, Belgium., Struyve M; Department of Gastroenterology, Ziekenhuis Oost-Limburg, Genk, Belgium., Deressa B; Department of Gastroenterology, CHU Brugmann, Brussels, Belgium., Sprengers D; Department of Gastroenterology, Ziekenhuis aan de Stroom, Antwerp, Belgium., de Vos M; Department of Gastroenterology, Hôpital de Jolimont HELORA, La Louvière, Belgium., Callens J; Department of Gastroenterology, AZ Klina, Brasschaat, Belgium., Shihao B; Department of Gastroenterology and Hepatology, Antwerp University Hospital, Antwerp, Belgium., Reynaert H; Department of Gastroenterology, UZ Brussels, Brussels, Belgium., Deltenre P; Department of Gastroenterology, Clinique Saint-Luc Bouge, Namur, Belgium., Janssens F; Department of Gastroenterology, Jessa Ziekenhuizen, Hasselt, Belgium., Negrin-Dastis S; Department of Gastroenterology, Grand Hôpital de Charleroi, Charleroi, Belgium., Stärkel P; Department of Gastroenterology, Clinique Universitaires Saint-Luc, Brussels, Belgium., Orlent H; Department of Gastroenterology and Hepatology, AZ Sint-Jan, Bruges, Belgium., Van Roey G; Department of Gastroenterology, AZ Turnhout, Turnhout, Belgium., Verhelst X; Department of Gastroenterology and Hepatology, Ghent University Hospital, Ghent, Belgium., Moreno C; Department of Gastroenterology, Hepatopancreatology and Digestive Oncology, CUB Hôpital Erasme, Brussels, Belgium., Delwaide J; Department of Hepato-Gastroenterology, CHU Sart-Tilman, Université de Liège, Liège, Belgium., Van Steenkiste C; Department of Gastroenterology, AZ Maria Middelares, Ghent, Belgium., Verlinden W; Department of Gastroenterology, Vitaz Sint-Niklaas, Sint-Niklaas, Belgium., Colle I; Department of Gastroenterology, AZORG, Aalst, Belgium., Plissonnier ML; Lyon Hepatology Institute, UMR Inserm U1350 PaThLiv, Université Claude Bernard Lyon 1, Hospices Civils de Lyon, Lyon, France., Mukadi BK; Department of Microbiology, Cliniques Universitaires Saint-Luc, Brussels, Belgium., Testoni B; Lyon Hepatology Institute, UMR Inserm U1350 PaThLiv, Université Claude Bernard Lyon 1, Hospices Civils de Lyon, Lyon, France., Zoulim F; Lyon Hepatology Institute, UMR Inserm U1350 PaThLiv, Université Claude Bernard Lyon 1, Hospices Civils de Lyon, Lyon, France., Matheeussen V; Laboratory of Medical Microbiology, Antwerp University Hospital, Antwerp, Belgium., Vanwolleghem T; Viral Hepatitis Research Group, Laboratory of Experimental Medicine and Pediatrics, University of Antwerp, Antwerp, Belgium.; Department of Gastroenterology and Hepatology, Antwerp University Hospital, Antwerp, Belgium.
Source: Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2026 Feb; Vol. 63 (3), pp. 352-361. Date of Electronic Publication: 2025 Nov 19.
Publication Type: Clinical Trial; Journal Article; Multicenter Study
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 8707234 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2036 (Electronic) Linking ISSN: 02692813 NLM ISO Abbreviation: Aliment Pharmacol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1365-2036
DOI:10.1111/apt.70465