Experimental evaluation of the therapeutic effect of niosomal miltefosine delivered via Polyvinylpyrrolidone - hyaluronic acid microneedle patches against Leishmania major.

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Title: Experimental evaluation of the therapeutic effect of niosomal miltefosine delivered via Polyvinylpyrrolidone - hyaluronic acid microneedle patches against Leishmania major.
Authors: Dastan N; Department of Parasitology and Mycology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran; Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: naghmehdastan81@gmail.com., Maghsood AH; Department of Parasitology and Mycology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran. Electronic address: a.h.maghsood@umsha.ac.ir., Hatam G; Basic Sciences in Infectious Diseases Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: hatamghr@sums.ac.ir., Jafari M; Center for Nanotechnology in Drug Delivery, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: Jafari.mahboob@gmail.com., Motavallihaghi SM; Department of Parasitology and Mycology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran. Electronic address: mousamotevalli@gmail.com., Derakhshanfar A; Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: derakhshanfar@sums.ac.ir., Ardeshiri H; Department of Medical Nanotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: hanyardesh@gmail.com., Tamaddon AM; Center for Nanotechnology in Drug Delivery, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: amtamadon@sums.ac.ir.
Source: International journal of biological macromolecules [Int J Biol Macromol] 2025 Dec; Vol. 334 (Pt 2), pp. 149139. Date of Electronic Publication: 2025 Nov 19.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-0003
DOI:10.1016/j.ijbiomac.2025.149139