Clinical significance of non-invasive in vitro drug sensitivity profiling using pancreatic cancer organoids derived from saline flushes collected during routine EUS-FNA.

Saved in:
Bibliographic Details
Title: Clinical significance of non-invasive in vitro drug sensitivity profiling using pancreatic cancer organoids derived from saline flushes collected during routine EUS-FNA.
Authors: Ekawa T; Department of Cancer Drug Discovery and Development, Research Centre, Osaka International Cancer Institute, Osaka, Japan. tomoya.ekawa@oici.jp.; Department of Cancer Immunotherapy, Research Centre, Osaka International Cancer Institute, Osaka, Japan. tomoya.ekawa@oici.jp., Ikezawa K; Department of Hepatobiliary and Pancreatic Oncology, Osaka International Cancer Institute, Osaka, Japan., Kukita Y; Laboratory of Genomic Pathology, Research Centre, Osaka International Cancer Institute, Osaka, Japan., Urabe M; Department of Hepatobiliary and Pancreatic Oncology, Osaka International Cancer Institute, Osaka, Japan., Kai Y; Department of Hepatobiliary and Pancreatic Oncology, Osaka International Cancer Institute, Osaka, Japan., Takada R; Department of Hepatobiliary and Pancreatic Oncology, Osaka International Cancer Institute, Osaka, Japan., Akazawa T; Department of Cancer Drug Discovery and Development, Research Centre, Osaka International Cancer Institute, Osaka, Japan.; Department of Cancer Immunotherapy, Research Centre, Osaka International Cancer Institute, Osaka, Japan., Mizote Y; Department of Cancer Drug Discovery and Development, Research Centre, Osaka International Cancer Institute, Osaka, Japan.; Department of Cancer Immunotherapy, Research Centre, Osaka International Cancer Institute, Osaka, Japan., Tatsumi K; Department of Cancer Drug Discovery and Development, Research Centre, Osaka International Cancer Institute, Osaka, Japan.; Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Medical Development, Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital, Kyoto, Japan., Nagata S; Department of Diagnostic Pathology and Cytology, Osaka International Cancer Institute, Osaka, Japan., Ogawa H; Nitto Joint Research Department for Nucleic Acid Medicine, Research Centre, Osaka International Cancer Institute, Osaka, Japan., Hasegawa S; Department of Gastroenterological Surgery, Osaka International Cancer Institute, Osaka, Japan., Takahashi H; Department of Gastroenterological Surgery, Osaka International Cancer Institute, Osaka, Japan., Ohkawa K; Department of Hepatobiliary and Pancreatic Oncology, Osaka International Cancer Institute, Osaka, Japan., Tahara H; Department of Cancer Drug Discovery and Development, Research Centre, Osaka International Cancer Institute, Osaka, Japan.; Centre for Clinical Research, Osaka International Cancer Institute, Osaka, Japan.
Source: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2026 May; Vol. 28 (5), pp. 1940-1946. Date of Electronic Publication: 2025 Nov 21.
Publication Type: Journal Article
Journal Info: Publisher: Springer Italia Country of Publication: Italy NLM ID: 101247119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1699-3055 (Electronic) Linking ISSN: 1699048X NLM ISO Abbreviation: Clin Transl Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41269488
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Clinical significance of non-invasive in vitro drug sensitivity profiling using pancreatic cancer organoids derived from saline flushes collected during routine EUS-FNA.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Ekawa+T%22">Ekawa T</searchLink>; Department of Cancer Drug Discovery and Development, Research Centre, Osaka International Cancer Institute, Osaka, Japan. tomoya.ekawa@oici.jp.; Department of Cancer Immunotherapy, Research Centre, Osaka International Cancer Institute, Osaka, Japan. tomoya.ekawa@oici.jp.<br /><searchLink fieldCode="AU" term="%22Ikezawa+K%22">Ikezawa K</searchLink>; Department of Hepatobiliary and Pancreatic Oncology, Osaka International Cancer Institute, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Kukita+Y%22">Kukita Y</searchLink>; Laboratory of Genomic Pathology, Research Centre, Osaka International Cancer Institute, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Urabe+M%22">Urabe M</searchLink>; Department of Hepatobiliary and Pancreatic Oncology, Osaka International Cancer Institute, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Kai+Y%22">Kai Y</searchLink>; Department of Hepatobiliary and Pancreatic Oncology, Osaka International Cancer Institute, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Takada+R%22">Takada R</searchLink>; Department of Hepatobiliary and Pancreatic Oncology, Osaka International Cancer Institute, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Akazawa+T%22">Akazawa T</searchLink>; Department of Cancer Drug Discovery and Development, Research Centre, Osaka International Cancer Institute, Osaka, Japan.; Department of Cancer Immunotherapy, Research Centre, Osaka International Cancer Institute, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Mizote+Y%22">Mizote Y</searchLink>; Department of Cancer Drug Discovery and Development, Research Centre, Osaka International Cancer Institute, Osaka, Japan.; Department of Cancer Immunotherapy, Research Centre, Osaka International Cancer Institute, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Tatsumi+K%22">Tatsumi K</searchLink>; Department of Cancer Drug Discovery and Development, Research Centre, Osaka International Cancer Institute, Osaka, Japan.; Department of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.; Department of Medical Development, Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Nagata+S%22">Nagata S</searchLink>; Department of Diagnostic Pathology and Cytology, Osaka International Cancer Institute, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Ogawa+H%22">Ogawa H</searchLink>; Nitto Joint Research Department for Nucleic Acid Medicine, Research Centre, Osaka International Cancer Institute, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Hasegawa+S%22">Hasegawa S</searchLink>; Department of Gastroenterological Surgery, Osaka International Cancer Institute, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Takahashi+H%22">Takahashi H</searchLink>; Department of Gastroenterological Surgery, Osaka International Cancer Institute, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Ohkawa+K%22">Ohkawa K</searchLink>; Department of Hepatobiliary and Pancreatic Oncology, Osaka International Cancer Institute, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Tahara+H%22">Tahara H</searchLink>; Department of Cancer Drug Discovery and Development, Research Centre, Osaka International Cancer Institute, Osaka, Japan.; Centre for Clinical Research, Osaka International Cancer Institute, Osaka, Japan.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101247119%22">Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico</searchLink> [Clin Transl Oncol] 2026 May; Vol. 28 (5), pp. 1940-1946. <i>Date of Electronic Publication: </i>2025 Nov 21.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Italia%22">Springer Italia </searchLink><i>Country of Publication: </i>Italy <i>NLM ID: </i>101247119 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1699-3055 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221699048X%22">1699048X </searchLink><i>NLM ISO Abbreviation: </i>Clin Transl Oncol <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41269488
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s12094-025-04111-9
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 1940
    Titles:
      – TitleFull: Clinical significance of non-invasive in vitro drug sensitivity profiling using pancreatic cancer organoids derived from saline flushes collected during routine EUS-FNA.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Ekawa T
      – PersonEntity:
          Name:
            NameFull: Ikezawa K
      – PersonEntity:
          Name:
            NameFull: Kukita Y
      – PersonEntity:
          Name:
            NameFull: Urabe M
      – PersonEntity:
          Name:
            NameFull: Kai Y
      – PersonEntity:
          Name:
            NameFull: Takada R
      – PersonEntity:
          Name:
            NameFull: Akazawa T
      – PersonEntity:
          Name:
            NameFull: Mizote Y
      – PersonEntity:
          Name:
            NameFull: Tatsumi K
      – PersonEntity:
          Name:
            NameFull: Nagata S
      – PersonEntity:
          Name:
            NameFull: Ogawa H
      – PersonEntity:
          Name:
            NameFull: Hasegawa S
      – PersonEntity:
          Name:
            NameFull: Takahashi H
      – PersonEntity:
          Name:
            NameFull: Ohkawa K
      – PersonEntity:
          Name:
            NameFull: Tahara H
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 05
              Text: 2026 May
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1699-3055
          Numbering:
            – Type: volume
              Value: 28
            – Type: issue
              Value: 5
          Titles:
            – TitleFull: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
              Type: main
ResultId 1