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PufA drives cholangiocarcinoma progression via NFκB signaling activation: a novel therapeutic target.

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Title: PufA drives cholangiocarcinoma progression via NFκB signaling activation: a novel therapeutic target.
Authors: Chen CP; Division of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.; College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.; Liver Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC., Hung TH; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan, ROC., Huang Y; College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan, ROC.; School of medicine, National Tsing Hua University, Hsinchu, Taiwan, ROC.; Department of Anatomic Pathology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan, ROC., Pan YR; College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.; Liver Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.; Department of General Surgery, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC., Yeh CN; College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.; Liver Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.; Department of General Surgery, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC., Huang WK; Division of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.; College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.; Liver Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC., Hsiao YT; Division of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.; Liver Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC., Lo CH; Division of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.; Liver Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC., Yu AL; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan, ROC., Yu J; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan, ROC. johnyu@gate.sinica.edu.tw., Wu CE; Division of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC. 8805017@cgmh.org.tw.; College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC. 8805017@cgmh.org.tw.; Liver Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC. 8805017@cgmh.org.tw.; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan, ROC. 8805017@cgmh.org.tw.; Division of Hematology-Oncology, Department of Internal Medicine, New Taipei Municipal TuCheng Hospital (Built and Operated by Chang Gung Medical Foundation), New Taipei City, Taiwan, ROC. 8805017@cgmh.org.tw.
Source: Cancer gene therapy [Cancer Gene Ther] 2026 Jan; Vol. 33 (1), pp. 132-144. Date of Electronic Publication: 2025 Nov 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9432230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5500 (Electronic) Linking ISSN: 09291903 NLM ISO Abbreviation: Cancer Gene Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: PufA drives cholangiocarcinoma progression via NFκB signaling activation: a novel therapeutic target.
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  Data: <searchLink fieldCode="AU" term="%22Chen+CP%22">Chen CP</searchLink>; Division of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.; College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.; Liver Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Hung+TH%22">Hung TH</searchLink>; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan, ROC.; School of medicine, National Tsing Hua University, Hsinchu, Taiwan, ROC.; Department of Anatomic Pathology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Pan+YR%22">Pan YR</searchLink>; College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.; Liver Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.; Department of General Surgery, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Yeh+CN%22">Yeh CN</searchLink>; College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.; Liver Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.; Department of General Surgery, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Huang+WK%22">Huang WK</searchLink>; Division of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.; College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.; Liver Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Hsiao+YT%22">Hsiao YT</searchLink>; Division of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.; Liver Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Lo+CH%22">Lo CH</searchLink>; Division of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.; Liver Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Yu+AL%22">Yu AL</searchLink>; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Yu+J%22">Yu J</searchLink>; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan, ROC. johnyu@gate.sinica.edu.tw.<br /><searchLink fieldCode="AU" term="%22Wu+CE%22">Wu CE</searchLink>; Division of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC. 8805017@cgmh.org.tw.; College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC. 8805017@cgmh.org.tw.; Liver Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC. 8805017@cgmh.org.tw.; Institute of Stem Cell and Translational Cancer Research, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan, ROC. 8805017@cgmh.org.tw.; Division of Hematology-Oncology, Department of Internal Medicine, New Taipei Municipal TuCheng Hospital (Built and Operated by Chang Gung Medical Foundation), New Taipei City, Taiwan, ROC. 8805017@cgmh.org.tw.
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  Data: <searchLink fieldCode="JN" term="%229432230%22">Cancer gene therapy</searchLink> [Cancer Gene Ther] 2026 Jan; Vol. 33 (1), pp. 132-144. <i>Date of Electronic Publication: </i>2025 Nov 22.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9432230 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5500 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209291903%22">09291903 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Gene Ther <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41417-025-00968-8
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        Text: English
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        StartPage: 132
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      – TitleFull: PufA drives cholangiocarcinoma progression via NFκB signaling activation: a novel therapeutic target.
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              Text: 2026 Jan
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