VRC01 Selects Rare HIV Escape Mutations After Acquisition in Antibody-Mediated Prevention Trials.

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Title: VRC01 Selects Rare HIV Escape Mutations After Acquisition in Antibody-Mediated Prevention Trials.
Authors: Williamson C; Division of Medical Virology, Institute of Infectious Disease and Molecular Medicine and Wellcome CIDRI-Africa Centre, Faculty of Health Sciences, University of Cape Town. Cape Town, South Africa.; National Health Laboratory Service, South Africa.; Centre for the AIDS Programme of Research in South Africa, University of Kwa-Zulu Natal, Durban, South Africa., Curry L; Division of Medical Virology, Institute of Infectious Disease and Molecular Medicine and Wellcome CIDRI-Africa Centre, Faculty of Health Sciences, University of Cape Town. Cape Town, South Africa., Mkhize NN; SA MRC Antibody Immunity Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.; National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa., Giorgi EE; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Magaret CA; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Lambson BE; SA MRC Antibody Immunity Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.; National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa., Hons SB; SA MRC Antibody Immunity Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.; National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa., Kaldine H; SA MRC Antibody Immunity Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.; National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa., Moyo-Gwete T; SA MRC Antibody Immunity Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.; National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa., Rolland M; US Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Rossenkhan R; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Garcia NMG; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Moodley C; Division of Medical Virology, Institute of Infectious Disease and Molecular Medicine and Wellcome CIDRI-Africa Centre, Faculty of Health Sciences, University of Cape Town. Cape Town, South Africa., Yssel A; Division of Medical Virology, Institute of Infectious Disease and Molecular Medicine and Wellcome CIDRI-Africa Centre, Faculty of Health Sciences, University of Cape Town. Cape Town, South Africa., Huang Y; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Marsden AA; SA MRC Antibody Immunity Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.; National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa., Reeves DB; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.; Department of Global Health, University of Washington, Seattle, WA, USA., Mayer BT; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Bumgarner RE; Department of Microbiology, University of Washington, Seattle, WA, USA., Beaume N; Division of Medical Virology, Institute of Infectious Disease and Molecular Medicine and Wellcome CIDRI-Africa Centre, Faculty of Health Sciences, University of Cape Town. Cape Town, South Africa., Westfall DH; Department of Microbiology, University of Washington, Seattle, WA, USA., Juraska M; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., DeCamp AC; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Murrell H; Division of Medical Virology, Institute of Infectious Disease and Molecular Medicine and Wellcome CIDRI-Africa Centre, Faculty of Health Sciences, University of Cape Town. Cape Town, South Africa., Bai H; US Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Deng W; Department of Microbiology, University of Washington, Seattle, WA, USA., Pankow AP; Department of Microbiology, University of Washington, Seattle, WA, USA., Bhattacharya T; Los Alamos National Laboratory, Los Alamos, NM, USA.; Santa Fe Institute, Santa Fe, NM, USA., York T; Division of Medical Virology, Institute of Infectious Disease and Molecular Medicine and Wellcome CIDRI-Africa Centre, Faculty of Health Sciences, University of Cape Town. Cape Town, South Africa., Ndabambi N; Division of Medical Virology, Institute of Infectious Disease and Molecular Medicine and Wellcome CIDRI-Africa Centre, Faculty of Health Sciences, University of Cape Town. Cape Town, South Africa., Chen L; Department of Microbiology, University of Washington, Seattle, WA, USA., Zhao H; Department of Microbiology, University of Washington, Seattle, WA, USA., Gwashu-Nyangiri A; Division of Medical Virology, Institute of Infectious Disease and Molecular Medicine and Wellcome CIDRI-Africa Centre, Faculty of Health Sciences, University of Cape Town. Cape Town, South Africa., Thebus R; Division of Medical Virology, Institute of Infectious Disease and Molecular Medicine and Wellcome CIDRI-Africa Centre, Faculty of Health Sciences, University of Cape Town. Cape Town, South Africa., Cohen P; Division of Medical Virology, Institute of Infectious Disease and Molecular Medicine and Wellcome CIDRI-Africa Centre, Faculty of Health Sciences, University of Cape Town. Cape Town, South Africa., Murrell B; Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Sweden., Karuna S; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Hural J; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Mgodi N; University of Zimbabwe College of Health Sciences Clinical Trials Research Centre, Harare, Zimbabwe., Edupuganti S; Department of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA., Morris L; SA MRC Antibody Immunity Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Montefiori D; Department of Surgery, Duke University Medical Center, Durham, NC, USA., McElrath MJ; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Cohen MS; Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Corey L; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Edlefsen PT; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Gilbert PB; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Moore PL; Centre for the AIDS Programme of Research in South Africa, University of Kwa-Zulu Natal, Durban, South Africa.; SA MRC Antibody Immunity Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.; National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.; Wits Infectious Diseases and Oncology Research Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Mullins JI; Department of Microbiology, University of Washington, Seattle, WA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Oct 29. Date of Electronic Publication: 2025 Oct 29.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.1101/2025.10.29.685411