X chromosome inactivation across primary human tissues is mostly complete, with significant implications for genetic and clinical studies.

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Bibliographic Details
Title: X chromosome inactivation across primary human tissues is mostly complete, with significant implications for genetic and clinical studies.
Authors: Shriner D; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA., Doumatey AP; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA., Lei L; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA., Gouveia MH; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA.; Department of Public Health Education, Morehouse School of Medicine, Atlanta, GA, USA., Meeks KAC; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA.; Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA., Heuston EF; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA., Zhou J; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA., Adeyemo AA; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA., Rotimi CN; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA. rotimic@mail.nih.gov.
Source: BMC genomics [BMC Genomics] 2025 Nov 24; Vol. 26 (1), pp. 1142. Date of Electronic Publication: 2025 Nov 24.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1471-2164
DOI:10.1186/s12864-025-12352-9