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X chromosome inactivation across primary human tissues is mostly complete, with significant implications for genetic and clinical studies.

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Title: X chromosome inactivation across primary human tissues is mostly complete, with significant implications for genetic and clinical studies.
Authors: Shriner D; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA., Doumatey AP; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA., Lei L; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA., Gouveia MH; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA.; Department of Public Health Education, Morehouse School of Medicine, Atlanta, GA, USA., Meeks KAC; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA.; Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA., Heuston EF; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA., Zhou J; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA., Adeyemo AA; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA., Rotimi CN; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA. rotimic@mail.nih.gov.
Source: BMC genomics [BMC Genomics] 2025 Nov 24; Vol. 26 (1), pp. 1142. Date of Electronic Publication: 2025 Nov 24.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: X chromosome inactivation across primary human tissues is mostly complete, with significant implications for genetic and clinical studies.
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  Data: <searchLink fieldCode="AU" term="%22Shriner+D%22">Shriner D</searchLink>; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Doumatey+AP%22">Doumatey AP</searchLink>; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lei+L%22">Lei L</searchLink>; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Gouveia+MH%22">Gouveia MH</searchLink>; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA.; Department of Public Health Education, Morehouse School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Meeks+KAC%22">Meeks KAC</searchLink>; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA.; Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Heuston+EF%22">Heuston EF</searchLink>; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Zhou+J%22">Zhou J</searchLink>; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Adeyemo+AA%22">Adeyemo AA</searchLink>; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Rotimi+CN%22">Rotimi CN</searchLink>; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD, USA. rotimic@mail.nih.gov.
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  Data: <searchLink fieldCode="JN" term="%22100965258%22">BMC genomics</searchLink> [BMC Genomics] 2025 Nov 24; Vol. 26 (1), pp. 1142. <i>Date of Electronic Publication: </i>2025 Nov 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100965258 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1471-2164 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214712164%22">14712164 </searchLink><i>NLM ISO Abbreviation: </i>BMC Genomics <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12864-025-12352-9
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        Text: English
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              Text: 2025 Nov 24
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