Vascular and Neural Transcriptomics Reveal Stage-Dependent Pathways to Inflammation and Cognitive Dysfunction in a Rat Model of Hypertension.

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Title: Vascular and Neural Transcriptomics Reveal Stage-Dependent Pathways to Inflammation and Cognitive Dysfunction in a Rat Model of Hypertension.
Authors: Arndt P; Department of Neurology Otto-von-Guericke University Magdeburg Germany.; German Center for Neurodegenerative Diseases (DZNE) within the Helmholtz Association Magdeburg Germany., Morton L; Institute of Inflammation and Neurodegeneration Otto-von-Guericke University Magdeburg Germany., Briese M; Institute of Clinical Neurobiology University Hospital Würzburg Würzburg Germany., Lämmlin N; Department of Neurology University Hospital Leipzig Leipzig Germany., Mattern H; German Center for Neurodegenerative Diseases (DZNE) within the Helmholtz Association Magdeburg Germany.; Biomedical Magnetic Resonance, Faculty of Natural Sciences Otto-von-Guericke University Magdeburg Germany., Hasanuzzaman M; Department of Neurology Otto-von-Guericke University Magdeburg Germany.; German Center for Neurodegenerative Diseases (DZNE) within the Helmholtz Association Magdeburg Germany., Westhues M; Department of Neurology Otto-von-Guericke University Magdeburg Germany.; German Center for Neurodegenerative Diseases (DZNE) within the Helmholtz Association Magdeburg Germany., Khoshneviszadeh M; Department of Neurology Otto-von-Guericke University Magdeburg Germany.; German Center for Neurodegenerative Diseases (DZNE) within the Helmholtz Association Magdeburg Germany., Appenzeller S; Comprehensive Cancer Center Mainfranken University Hospital Würzburg Würzburg Germany., Gündel D; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research Department of Neuroradiopharmaceuticals Leipzig Germany., Toussaint M; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research Department of Neuroradiopharmaceuticals Leipzig Germany., Brust P; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research Department of Neuroradiopharmaceuticals Leipzig Germany., Kniess T; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research Department of Radiopharmaceutical and Chemical Biology Dresden Germany., Oelschlegel A; Leibniz-Institute for Neurobiology Magdeburg Germany., Goldschmidt J; Leibniz-Institute for Neurobiology Magdeburg Germany.; Center for Behavioral Brain Sciences (CBBS) Magdeburg Germany., Meuth S; Department of Neurology Heinrich-Heine-University Düsseldorf Germany., Müller P; Department of Cardiology Otto-von-Guericke University Magdeburg Germany., Braun-Dullaeus R; Department of Cardiology Otto-von-Guericke University Magdeburg Germany., Debska-Vielhaber G; Department of Neurology Otto-von-Guericke University Magdeburg Germany., Vielhaber S; Department of Neurology Otto-von-Guericke University Magdeburg Germany., Becker A; Institute of Pharmacology and Toxicology Otto-von-Guericke University Magdeburg Germany., Dityatev A; German Center for Neurodegenerative Diseases (DZNE) within the Helmholtz Association Magdeburg Germany.; Center for Behavioral Brain Sciences (CBBS) Magdeburg Germany.; Medical Faculty Otto-von-Guericke University Magdeburg Germany., Henneicke S; Department of Neurology Otto-von-Guericke University Magdeburg Germany.; German Center for Neurodegenerative Diseases (DZNE) within the Helmholtz Association Magdeburg Germany., Sendtner M; Institute of Clinical Neurobiology University Hospital Würzburg Würzburg Germany., Dunay I; Institute of Inflammation and Neurodegeneration Otto-von-Guericke University Magdeburg Germany., Schreiber S; Department of Neurology Otto-von-Guericke University Magdeburg Germany.; German Center for Neurodegenerative Diseases (DZNE) within the Helmholtz Association Magdeburg Germany.; Center for Behavioral Brain Sciences (CBBS) Magdeburg Germany.
Source: Journal of the American Heart Association [J Am Heart Assoc] 2026 Mar 17; Vol. 15 (6), pp. e040710. Date of Electronic Publication: 2025 Nov 26.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2047-9980
DOI:10.1161/JAHA.125.040710