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Continuous indices to assess the phenotypic spectrum of kidney transplant rejection.

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Title: Continuous indices to assess the phenotypic spectrum of kidney transplant rejection.
Authors: Vaulet T; Nephrology and Renal Transplantation Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium., Koshy P; Nephrology and Renal Transplantation Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.; Department of Imaging and Pathology, Translational Cell and Tissue Research, KU Leuven, Leuven, Belgium.; Department of Nephrology and Renal Transplantation, University Hospitals Leuven, Leuven, Belgium., Wellekens K; Nephrology and Renal Transplantation Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.; Department of Nephrology and Renal Transplantation, University Hospitals Leuven, Leuven, Belgium., Aubert O; Université Paris Cité, Inserm UMR1151, Necker Enfants Malades Institute (INEM), Paris, France.; Department of Kidney and Metabolic Diseases, Transplantation and Clinical Immunology, Necker Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France., Bottomley C; Department of Immunology and Inflammation, Imperial College, London, United Kingdom., Callemeyn J; Nephrology and Renal Transplantation Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.; Department of Nephrology and Renal Transplantation, University Hospitals Leuven, Leuven, Belgium., Cleenders E; Nephrology and Renal Transplantation Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.; Leuven Biostatistics and Statistical Bioinformatics Centre, Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium., Coemans M; Nephrology and Renal Transplantation Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.; Leuven Biostatistics and Statistical Bioinformatics Centre, Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium., Cornell L; Department of Pathology & Laboratory Medicine and Department of Medicine at the University of Calgary, Calgary, Alberta, Canada., de Vries APJ; Division of Nephrology, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands.; Leiden Transplant Center, Leiden University Medical Center, Leiden, the Netherlands., Divard G; Université Paris Cité, INSERM U970 PARCC, Paris Institute for Transplantation and Organ Regeneration, Paris, France., Emonds MP; Histocompatibility and Immunogenetics Laboratory, Belgian Red Cross-Flanders, Mechelen, Belgium., Florquin S; Amsterdam UMC, University of Amsterdam, Dept. of Pathology, Amsterdam, The Netherlands.; Amsterdam Institute for Infection and Immunology, Amsterdam, The Netherlands., Haas M; Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA., Halloran PF; Department of Medicine, University of Alberta, Edmonton, AB, Canada., Kers J; Division of Nephrology, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands.; Leiden Transplant Center, Leiden University Medical Center, Leiden, the Netherlands.; Department of Pathology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.; Department of Pathology, Leiden Transplant Center, Leiden University Medical Center, Leiden, Netherlands.; Van 't Hoff Institute for Molecular Sciences, University of Amsterdam, Amsterdam, Netherlands., Kuypers D; Nephrology and Renal Transplantation Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.; Department of Nephrology and Renal Transplantation, University Hospitals Leuven, Leuven, Belgium., Muthukumar T; Division of Nephrology and Hypertension, Weill Cornell Medicine, New York, NY, USA., Pagliazzi A; Nephrology and Renal Transplantation Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.; Department of Nephrology and Renal Transplantation, University Hospitals Leuven, Leuven, Belgium., Salvatore S; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Thaunat O; CIRI, INSERM U1111, Université Claude Bernard Lyon I, CNRS UMR5308, Ecole Normale Supérieure de Lyon, Univ. Lyon, Lyon, France.; Department of Transplantation, Nephrology, and Clinical Immunology, Hospices Civils de Lyon, Edouard Herriot Hospital, Lyon, France., Seshan SV; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA., Van Loon E; Nephrology and Renal Transplantation Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.; Department of Nephrology and Renal Transplantation, University Hospitals Leuven, Leuven, Belgium., Vanhoutte T; Nephrology and Renal Transplantation Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.; Department of Nephrology and Renal Transplantation, University Hospitals Leuven, Leuven, Belgium., Böhmig GA; Division of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria., von Samson-Himmelstjerna FA; Department of Nephrology and Hypertension, University Hospital Schleswig-Holstein-Campus Kiel, Kiel, Germany., Willicombe M; Department of Immunology and Inflammation, Imperial College, London, United Kingdom., Cherukuri A; Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA, USA., Loupy A; Université Paris Cité, INSERM U970 PARCC, Paris Institute for Transplantation and Organ Regeneration, Paris, France., Roufosse C; Department of Immunology and Inflammation, Imperial College, London, United Kingdom., Naesens M; Nephrology and Renal Transplantation Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium. maarten.naesens@kuleuven.be.; Department of Nephrology and Renal Transplantation, University Hospitals Leuven, Leuven, Belgium. maarten.naesens@kuleuven.be.
Source: Nature communications [Nat Commun] 2025 Nov 26; Vol. 16 (1), pp. 10417. Date of Electronic Publication: 2025 Nov 26.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-65153-9