Integrative neuroimmunology reveals leukocyte-expressing PAX6 as a critical predictor of major depressive disorder.

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Bibliographic Details
Title: Integrative neuroimmunology reveals leukocyte-expressing PAX6 as a critical predictor of major depressive disorder.
Authors: Dias HD; Department of Medicine, Division of Molecular Medicine, Laboratory of Medical Investigation 29, University of São Paulo (USP) School of Medicine, São Paulo, Brazil. haroldodd@gmail.com.; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. haroldodd@gmail.com., Adri AS; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo (USP), São Paulo, SP, Brazil., Nóbile AL; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo (USP), São Paulo, SP, Brazil., de Oliveira MG; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Chung EN; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; The Gene Lay Institute of Immunology and Inflammation, Boston, MA, USA., Bahia IAF; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil., Fonseca DLM; Interunit Postgraduate Program on Bioinformatics, Institute of Mathematics and Statistics (IME), University of Sao Paulo (USP), Sao Paulo, SP, Brazil., Schimke LF; Bioinformatics Multidisciplinary Environment, Federal University of Rio Grande do Norte, Natal, Brazil., Filgueiras IS; Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil., Marçal P; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo (USP), São Paulo, SP, Brazil., do Vale FYN; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo (USP), São Paulo, SP, Brazil., Dalmolin RJS; Bioinformatics Multidisciplinary Environment, Federal University of Rio Grande do Norte, Natal, Brazil., Cabral-Miranda G; The Gene Lay Institute of Immunology and Inflammation, Boston, MA, USA., Lee J; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; The Gene Lay Institute of Immunology and Inflammation, Boston, MA, USA., Nakaya H; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo (USP), São Paulo, SP, Brazil.; Instituto Israelita de Ensino e Pesquisa Albert Einstein, Hospital Israelita Albert Einstein, São Paulo, Brazil., Marques AHC; Bioinformatics Multidisciplinary Environment, Federal University of Rio Grande do Norte, Natal, Brazil., Bortoloti R; Department of Medicine, Division of Molecular Medicine, Laboratory of Medical Investigation 29, University of São Paulo (USP) School of Medicine, São Paulo, Brazil., Hamani C; Sunnybrook Research Institute, Harquail Centre for Neuromodulation, Division of Neurosurgery, University of Toronto, Toronto, ON, M4N3M5, Canada., Wheeler MA; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; The Gene Lay Institute of Immunology and Inflammation, Boston, MA, USA., Rezende RM; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. rmachadorezende@bwh.harvard.edu., Cabral-Marques O; Department of Medicine, Division of Molecular Medicine, Laboratory of Medical Investigation 29, University of São Paulo (USP) School of Medicine, São Paulo, Brazil. otavio.cmarques@usp.br.; Interunit Postgraduate Program on Bioinformatics, Institute of Mathematics and Statistics (IME), University of Sao Paulo (USP), Sao Paulo, SP, Brazil. otavio.cmarques@usp.br.; Bioinformatics Multidisciplinary Environment, Federal University of Rio Grande do Norte, Natal, Brazil. otavio.cmarques@usp.br.; D'Or Institute for Research and Education (IDOR), São Paulo, Brazil. otavio.cmarques@usp.br.
Source: Translational psychiatry [Transl Psychiatry] 2025 Nov 29; Vol. 16 (1), pp. 35. Date of Electronic Publication: 2025 Nov 29.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2158-3188
DOI:10.1038/s41398-025-03776-8