Dissecting Fear and Emotional Pain in Posttraumatic Stress Disorder: From Symptom Networks to Neural Signatures.

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Title: Dissecting Fear and Emotional Pain in Posttraumatic Stress Disorder: From Symptom Networks to Neural Signatures.
Authors: Ben-Zion Z; Department of Comparative Medicine, Yale School of Medicine, New Haven, Connecticut; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut; U.S. Department of Veterans Affairs National Center for PTSD, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven, Connecticut; School of Public Health, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel. Electronic address: ziv.ben-zion@yale.edu., Basol EZ; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut; U.S. Department of Veterans Affairs National Center for PTSD, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven, Connecticut., Simon AJ; Department of Radiology, Yale School of Medicine, New Haven, Connecticut; Department of Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut., Abargil M; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut; U.S. Department of Veterans Affairs National Center for PTSD, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven, Connecticut., Samonek K; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut; U.S. Department of Veterans Affairs National Center for PTSD, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven, Connecticut., Paterson M; Department of Comparative Medicine, Yale School of Medicine, New Haven, Connecticut., Spiller TR; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut; Department of Adult Psychiatry and Psychotherapy, Psychiatric University Clinic Zurich, Zurich, Switzerland; University of Zurich, Zurich, Switzerland., Duek O; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut; U.S. Department of Veterans Affairs National Center for PTSD, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven, Connecticut; Department of Epidemiology, Biostatistics, and Community Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel., Just S; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany., Preller K; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany; Boehringer Ingelheim (Schweiz) GmbH, Basel, Switzerland., Keynan JN; Sagol Brain Institute Tel-Aviv, Wohl Institute for Advanced Imaging, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel., Admon R; School of Psychological Sciences, University of Haifa, Haifa, Israel., Liberzon I; Department of Psychiatry, College of Medicine, Texas A&M University, College Station, Texas., Shalev AY; Department of Psychiatry, NYU Grossman School of Medicine, New York, New York., Hendler T; Sagol Brain Institute Tel-Aviv, Wohl Institute for Advanced Imaging, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel; Sagol School of Neuroscience, Faculty of Social Sciences & Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel., Levy I; Department of Comparative Medicine, Yale School of Medicine, New Haven, Connecticut; Department of Psychology, Yale University, New Haven, Connecticut; Wu Tsai Institute, Yale University, New Haven, Connecticut., Joormann J; Department of Psychology, Yale University, New Haven, Connecticut; Wu Tsai Institute, Yale University, New Haven, Connecticut., Scheinost D; Department of Radiology, Yale School of Medicine, New Haven, Connecticut; Department of Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut; Wu Tsai Institute, Yale University, New Haven, Connecticut., Harpaz-Rotem I; Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut; U.S. Department of Veterans Affairs National Center for PTSD, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven, Connecticut; Department of Psychology, Yale University, New Haven, Connecticut; Wu Tsai Institute, Yale University, New Haven, Connecticut.
Source: Biological psychiatry [Biol Psychiatry] 2026 Jul 01; Vol. 100 (1), pp. 111-121. Date of Electronic Publication: 2025 Nov 29.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0213264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2402 (Electronic) Linking ISSN: 00063223 NLM ISO Abbreviation: Biol Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-2402
DOI:10.1016/j.biopsych.2025.11.016