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[18F]FDG PET/CT as a biomarker for response evaluation in neoadjuvant treatment of early breast cancer: could it become a game-changer in the scenario of the emerging (de)-escalation strategies?

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Title: [18F]FDG PET/CT as a biomarker for response evaluation in neoadjuvant treatment of early breast cancer: could it become a game-changer in the scenario of the emerging (de)-escalation strategies?
Authors: Gerosa R; Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano, MI, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, Italy., Gelardi F; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, Italy.; Vita-Salute San Raffaele University, Milan, Italy.; IRCCS San Raffaele Hospital, Milan, Italy., Tiberio P; Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano, MI, Italy., Jacobs F; Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano, MI, Italy., Benvenuti C; Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano, MI, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, Italy., Gaudio M; Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano, MI, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, Italy., Canzian J; Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano, MI, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, Italy., Tinterri B; Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano, MI, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, Italy., Zambelli A; Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano, MI, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, Italy.; Medical Oncology Unit, ASST Papa Giovanni XXIII, Piazza OMS 1, 24127, Bergamo, Italy., Santoro A; Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano, MI, Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, Italy., Antunovic L; IRCCS San Raffaele Hospital, Milan, Italy., De Sanctis R; Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano, MI, Italy. rdesanctis@asst-pg23.it.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, Italy. rdesanctis@asst-pg23.it.; Medical Oncology Unit, ASST Papa Giovanni XXIII, Piazza OMS 1, 24127, Bergamo, Italy. rdesanctis@asst-pg23.it.
Source: La Radiologia medica [Radiol Med] 2026 Apr; Vol. 131 (4), pp. 582-596. Date of Electronic Publication: 2025 Dec 01.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer Milan Country of Publication: Italy NLM ID: 0177625 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1826-6983 (Electronic) Linking ISSN: 00338362 NLM ISO Abbreviation: Radiol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1826-6983
DOI:10.1007/s11547-025-02138-0